The Many Faces of Tau

Meaghan Morris, Sumihiro Maeda, Keith Vossel, Lennart Mucke

Research output: Contribution to journalReview article

476 Citations (Scopus)

Abstract

While the microtubule-binding capacity of the protein tau has been known for many years, new functions of tau in signaling and cytoskeletal organization have recently emerged. In this review, we highlight these functions and the potential roles of tau in neurodegenerative disease. We also discuss the therapeutic potential of drugs targeting various aspects of tau biology.

Original languageEnglish
Pages (from-to)410-426
Number of pages17
JournalNeuron
Volume70
Issue number3
DOIs
Publication statusPublished - 2011 May 12

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ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Morris, M., Maeda, S., Vossel, K., & Mucke, L. (2011). The Many Faces of Tau. Neuron, 70(3), 410-426. https://doi.org/10.1016/j.neuron.2011.04.009