Abstract
A 56-year-old man underwent extrapleural pneumonectomy for malignant pleural mesothelioma (MPM). The histological diagnosis was epithelioid mesothelioma with T2N0M0, and no sarcomatoid component was observed. Subsequently, 14years after complete resection, screening computed tomography detected a rapidly growing right thoracic mass, which was diagnosed as a recurrence of MPM on resection. However, it was composed of both epithelioid (50%) and sarcomatoid (50%) components, suggesting possible histological transformation. Although there have been some previous reports on the recurrence of MPM, to the best of our knowledge, this is the first clinical case which indicated that histological transformation of MPM might occur.
| Original language | English |
|---|---|
| Pages (from-to) | 754-757 |
| Number of pages | 4 |
| Journal | Pathology International |
| Volume | 62 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 2012 Nov |
| Externally published | Yes |
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Keywords
- Biphasic type
- Epithelioid type
- Histological transformation
- Mesothelioma
- Sarcomatoid type
ASJC Scopus subject areas
- Pathology and Forensic Medicine
Cite this
The recurrence of malignant pleural mesothelioma 14 years after extrapleural pneumonectomy : Possible histological transformation. / Kinoshita, Tomonari; Ishii, Genichiro; Matsumura, Yuki; Shiozawa, Toshihiro; Aokage, Keiju; Hishida, Tomoyuki; Yoshida, Junji; Nagai, Kanji.
In: Pathology International, Vol. 62, No. 11, 11.2012, p. 754-757.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The recurrence of malignant pleural mesothelioma 14 years after extrapleural pneumonectomy
T2 - Possible histological transformation
AU - Kinoshita, Tomonari
AU - Ishii, Genichiro
AU - Matsumura, Yuki
AU - Shiozawa, Toshihiro
AU - Aokage, Keiju
AU - Hishida, Tomoyuki
AU - Yoshida, Junji
AU - Nagai, Kanji
PY - 2012/11
Y1 - 2012/11
N2 - A 56-year-old man underwent extrapleural pneumonectomy for malignant pleural mesothelioma (MPM). The histological diagnosis was epithelioid mesothelioma with T2N0M0, and no sarcomatoid component was observed. Subsequently, 14years after complete resection, screening computed tomography detected a rapidly growing right thoracic mass, which was diagnosed as a recurrence of MPM on resection. However, it was composed of both epithelioid (50%) and sarcomatoid (50%) components, suggesting possible histological transformation. Although there have been some previous reports on the recurrence of MPM, to the best of our knowledge, this is the first clinical case which indicated that histological transformation of MPM might occur.
AB - A 56-year-old man underwent extrapleural pneumonectomy for malignant pleural mesothelioma (MPM). The histological diagnosis was epithelioid mesothelioma with T2N0M0, and no sarcomatoid component was observed. Subsequently, 14years after complete resection, screening computed tomography detected a rapidly growing right thoracic mass, which was diagnosed as a recurrence of MPM on resection. However, it was composed of both epithelioid (50%) and sarcomatoid (50%) components, suggesting possible histological transformation. Although there have been some previous reports on the recurrence of MPM, to the best of our knowledge, this is the first clinical case which indicated that histological transformation of MPM might occur.
KW - Biphasic type
KW - Epithelioid type
KW - Histological transformation
KW - Mesothelioma
KW - Sarcomatoid type
UR - http://www.scopus.com/inward/record.url?scp=84868315883&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84868315883&partnerID=8YFLogxK
U2 - 10.1111/pin.12003
DO - 10.1111/pin.12003
M3 - Article
C2 - 23121607
AN - SCOPUS:84868315883
VL - 62
SP - 754
EP - 757
JO - Pathology International
JF - Pathology International
SN - 1320-5463
IS - 11
ER -