The relation of conjunctival and corneal findings in severe ocular allergies

Mari Tanaka, Murat Dogru, Yoji Takano, Minori Miyake-Kashima, Naoko Asano-Kato, Kazumi Fukagawa, Kazuo Tsubota, Hiroshi Fujishima

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Objective: Corneal lesions such as ulcers and erosions are major complications observed in patients with severe ocular allergic diseases. We aimed to look into the relationship between specific clinical conjunctival findings and the severity of corneal complications. Methods: Thirty eyes of 6 patients with vernal keratoconjunctivitis (VKC) and 13 patients with atopic keratoconjunctivitis (AKC) were evaluated in this study. Slit-lamp photographs of upper tarsal conjunctiva and cornea were used to evaluate the clinical findings objectively. The corneal findings and clinical findings of upper tarsal conjunctiva such as conjunctival injection, edema, the height of papillae, and mucous discharge were evaluated and graded. Statistical correlations between conjunctival findings and the severity of corneal damage were analyzed. Results: Conjunctival injection and edema significantly correlated with the severity of corneal complications. The height of the papillae and the amount of mucous discharge did not correlate with the severity of corneal complications. Conclusion: Direct signs of inflammation such as injection and edema correlated with corneal damage. The height of papillae did not show a significant correlation with the corneal findings. Our results suggest that inflammation of the conjunctiva rather than mechanical factors may play a greater role in the formation of corneal damage in severe ocular allergies.

Original languageEnglish
Pages (from-to)464-467
Number of pages4
JournalCornea
Volume23
Issue number5
DOIs
Publication statusPublished - 2004 Jul
Externally publishedYes

Fingerprint

Conjunctiva
Edema
Hypersensitivity
Injections
Keratoconjunctivitis
Inflammation
Allergic Conjunctivitis
Eye Diseases
Cornea
Ulcer
Corneal Injuries

Keywords

  • Cobblestone-like papillae
  • Conjunctival inflammation
  • Corneal damage
  • Ocular allergy

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Tanaka, M., Dogru, M., Takano, Y., Miyake-Kashima, M., Asano-Kato, N., Fukagawa, K., ... Fujishima, H. (2004). The relation of conjunctival and corneal findings in severe ocular allergies. Cornea, 23(5), 464-467. https://doi.org/10.1097/01.ico.0000114836.13127.45

The relation of conjunctival and corneal findings in severe ocular allergies. / Tanaka, Mari; Dogru, Murat; Takano, Yoji; Miyake-Kashima, Minori; Asano-Kato, Naoko; Fukagawa, Kazumi; Tsubota, Kazuo; Fujishima, Hiroshi.

In: Cornea, Vol. 23, No. 5, 07.2004, p. 464-467.

Research output: Contribution to journalArticle

Tanaka, M, Dogru, M, Takano, Y, Miyake-Kashima, M, Asano-Kato, N, Fukagawa, K, Tsubota, K & Fujishima, H 2004, 'The relation of conjunctival and corneal findings in severe ocular allergies', Cornea, vol. 23, no. 5, pp. 464-467. https://doi.org/10.1097/01.ico.0000114836.13127.45
Tanaka M, Dogru M, Takano Y, Miyake-Kashima M, Asano-Kato N, Fukagawa K et al. The relation of conjunctival and corneal findings in severe ocular allergies. Cornea. 2004 Jul;23(5):464-467. https://doi.org/10.1097/01.ico.0000114836.13127.45
Tanaka, Mari ; Dogru, Murat ; Takano, Yoji ; Miyake-Kashima, Minori ; Asano-Kato, Naoko ; Fukagawa, Kazumi ; Tsubota, Kazuo ; Fujishima, Hiroshi. / The relation of conjunctival and corneal findings in severe ocular allergies. In: Cornea. 2004 ; Vol. 23, No. 5. pp. 464-467.
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