The Relation of Ocular Surface Irregularity and Visual Disturbance in Early Stage Acanthamoeba Keratitis

Yukihiro Matsumoto, Asako Kodama, Eiki Goto, Tetsuya Kawakita, Murat Dogru, Kazuo Tsubota

Research output: Contribution to journalArticle

Abstract

PURPOSE:: To evaluate the relation between ocular surface irregularity and visual disturbance in early stage Acanthamoeba keratitis (AK). METHODS:: Fifteen patients with culture-proven AK underwent routine ophthalmic examinations, including best-corrected visual acuity (BCVA) measurement, slitlamp biomicroscope examination, and corneal fluorescein dye staining test, in both the eyes. We also evaluated the corneal sensitivity with Cochet-Bonnet esthesiometer, tear functions by Schirmerʼs test, and ocular surface irregularity by corneal topography and compared the results with the contralateral healthy eyes in this study. RESULTS:: The mean logarithm of the minimum angle of resolution BCVA (0.71±0.77) was significantly lower in the eyes with AK (P=0.002). Epithelial disorders were present in all eyes, and radial keratoneuritis in 14 eyes (93.3%). The mean corneal sensitivity (39.3±24.1 mm) was significantly lower in eyes with AK compared with the healthy eyes (P=0.005). The mean Schirmerʼs test value (22.5±12.0 mm) in eyes with AK was significantly higher compared with the healthy eyes (P=0.01). The ocular surface irregularity indices (the surface regularity index, 2.47±0.42; the surface asymmetry index, 3.24±1.31) were significantly higher in eyes with AK compared with contralateral healthy eyes (P

Original languageEnglish
JournalEye and Contact Lens
DOIs
Publication statusAccepted/In press - 2016 Jan 16

Fingerprint

Acanthamoeba Keratitis
Visual Acuity
Corneal Topography

ASJC Scopus subject areas

  • Ophthalmology

Cite this

The Relation of Ocular Surface Irregularity and Visual Disturbance in Early Stage Acanthamoeba Keratitis. / Matsumoto, Yukihiro; Kodama, Asako; Goto, Eiki; Kawakita, Tetsuya; Dogru, Murat; Tsubota, Kazuo.

In: Eye and Contact Lens, 16.01.2016.

Research output: Contribution to journalArticle

Matsumoto, Yukihiro ; Kodama, Asako ; Goto, Eiki ; Kawakita, Tetsuya ; Dogru, Murat ; Tsubota, Kazuo. / The Relation of Ocular Surface Irregularity and Visual Disturbance in Early Stage Acanthamoeba Keratitis. In: Eye and Contact Lens. 2016.
@article{eedd39848cfd4c3c97f88f15e1919b22,
title = "The Relation of Ocular Surface Irregularity and Visual Disturbance in Early Stage Acanthamoeba Keratitis",
abstract = "PURPOSE:: To evaluate the relation between ocular surface irregularity and visual disturbance in early stage Acanthamoeba keratitis (AK). METHODS:: Fifteen patients with culture-proven AK underwent routine ophthalmic examinations, including best-corrected visual acuity (BCVA) measurement, slitlamp biomicroscope examination, and corneal fluorescein dye staining test, in both the eyes. We also evaluated the corneal sensitivity with Cochet-Bonnet esthesiometer, tear functions by Schirmerʼs test, and ocular surface irregularity by corneal topography and compared the results with the contralateral healthy eyes in this study. RESULTS:: The mean logarithm of the minimum angle of resolution BCVA (0.71±0.77) was significantly lower in the eyes with AK (P=0.002). Epithelial disorders were present in all eyes, and radial keratoneuritis in 14 eyes (93.3{\%}). The mean corneal sensitivity (39.3±24.1 mm) was significantly lower in eyes with AK compared with the healthy eyes (P=0.005). The mean Schirmerʼs test value (22.5±12.0 mm) in eyes with AK was significantly higher compared with the healthy eyes (P=0.01). The ocular surface irregularity indices (the surface regularity index, 2.47±0.42; the surface asymmetry index, 3.24±1.31) were significantly higher in eyes with AK compared with contralateral healthy eyes (P",
author = "Yukihiro Matsumoto and Asako Kodama and Eiki Goto and Tetsuya Kawakita and Murat Dogru and Kazuo Tsubota",
year = "2016",
month = "1",
day = "16",
doi = "10.1097/ICL.0000000000000233",
language = "English",
journal = "Eye and Contact Lense",
issn = "1542-2321",
publisher = "Lippincott Williams and Wilkins",

}

TY - JOUR

T1 - The Relation of Ocular Surface Irregularity and Visual Disturbance in Early Stage Acanthamoeba Keratitis

AU - Matsumoto, Yukihiro

AU - Kodama, Asako

AU - Goto, Eiki

AU - Kawakita, Tetsuya

AU - Dogru, Murat

AU - Tsubota, Kazuo

PY - 2016/1/16

Y1 - 2016/1/16

N2 - PURPOSE:: To evaluate the relation between ocular surface irregularity and visual disturbance in early stage Acanthamoeba keratitis (AK). METHODS:: Fifteen patients with culture-proven AK underwent routine ophthalmic examinations, including best-corrected visual acuity (BCVA) measurement, slitlamp biomicroscope examination, and corneal fluorescein dye staining test, in both the eyes. We also evaluated the corneal sensitivity with Cochet-Bonnet esthesiometer, tear functions by Schirmerʼs test, and ocular surface irregularity by corneal topography and compared the results with the contralateral healthy eyes in this study. RESULTS:: The mean logarithm of the minimum angle of resolution BCVA (0.71±0.77) was significantly lower in the eyes with AK (P=0.002). Epithelial disorders were present in all eyes, and radial keratoneuritis in 14 eyes (93.3%). The mean corneal sensitivity (39.3±24.1 mm) was significantly lower in eyes with AK compared with the healthy eyes (P=0.005). The mean Schirmerʼs test value (22.5±12.0 mm) in eyes with AK was significantly higher compared with the healthy eyes (P=0.01). The ocular surface irregularity indices (the surface regularity index, 2.47±0.42; the surface asymmetry index, 3.24±1.31) were significantly higher in eyes with AK compared with contralateral healthy eyes (P

AB - PURPOSE:: To evaluate the relation between ocular surface irregularity and visual disturbance in early stage Acanthamoeba keratitis (AK). METHODS:: Fifteen patients with culture-proven AK underwent routine ophthalmic examinations, including best-corrected visual acuity (BCVA) measurement, slitlamp biomicroscope examination, and corneal fluorescein dye staining test, in both the eyes. We also evaluated the corneal sensitivity with Cochet-Bonnet esthesiometer, tear functions by Schirmerʼs test, and ocular surface irregularity by corneal topography and compared the results with the contralateral healthy eyes in this study. RESULTS:: The mean logarithm of the minimum angle of resolution BCVA (0.71±0.77) was significantly lower in the eyes with AK (P=0.002). Epithelial disorders were present in all eyes, and radial keratoneuritis in 14 eyes (93.3%). The mean corneal sensitivity (39.3±24.1 mm) was significantly lower in eyes with AK compared with the healthy eyes (P=0.005). The mean Schirmerʼs test value (22.5±12.0 mm) in eyes with AK was significantly higher compared with the healthy eyes (P=0.01). The ocular surface irregularity indices (the surface regularity index, 2.47±0.42; the surface asymmetry index, 3.24±1.31) were significantly higher in eyes with AK compared with contralateral healthy eyes (P

UR - http://www.scopus.com/inward/record.url?scp=84954487498&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84954487498&partnerID=8YFLogxK

U2 - 10.1097/ICL.0000000000000233

DO - 10.1097/ICL.0000000000000233

M3 - Article

JO - Eye and Contact Lense

JF - Eye and Contact Lense

SN - 1542-2321

ER -