The role of contrast-enhanced high resolution MRI in the surgical planning of breast cancer

Hideko Hiramatsu, Kohji Enomoto, Tadashi Ikeda, Makio Mukai, Junji Furukawa, Kiyoshi Kikuchi, Koichi Oshio, Nobuyoshi Hiraoka, Masaki Kitajima, Kyoichi Hiramatsu

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The role of contrast-enhanced high resolution MRI for planning surgery in breast cancer was evaluated. Of 72 patients examined, 57 patients had invasive ductal carcinoma, 2 had mucinous carcinoma, 1 had medullary carcinoma, 7 had invasive lobular carcinoma, 2 had ductal carcinoma in situ (DCIS) and 3 had Paget's disease. A 1.5 T Signa imager (GE Medical Systems, Milwaukee, WI) was used with a dedicated breast coil. The pulse sequence based on RARE (rapid acquisition with relaxation enhancement) was used with a fat suppression technique. After examining both breasts, the affected breast alone was examined with Gd enhancement. Linear and/or spotty enhancement on MRI was considered to suggest DCIS or intraductal spread in the area surrounding the invasive cancer. Of 72 patients, 50 showed linear and/or spotty enhancement on MRI and 41 of those 50 patients had DCIS or intraductal spread. In contrast, 22 of 72 patients were considered to have little or no intraductal spread on MRI and 17 of the 22 patients had no or little intraductal spread on pathological examination. The sensitivity, specificity and accuracy for detecting intraductal spread on MRI were 89%, 82% and 81%, respectively. Discrepancies in the estimated extent of intraductal spread were less than 2 cm in 90% of the patients according to pathological mapping. High resolution MRI was considered useful in detecting intraductal spread and in estimating its extent, however, larger study using precise correlation with pathology is necessary.

Original languageEnglish
Pages (from-to)285-290
Number of pages6
JournalBreast Cancer
Volume4
Issue number4
DOIs
Publication statusPublished - 1997 Dec

Fingerprint

Breast Neoplasms
Carcinoma, Intraductal, Noninfiltrating
Breast
Lobular Carcinoma
Mucinous Adenocarcinoma
Ductal Carcinoma
Medullary Carcinoma
Fats
Pathology
Sensitivity and Specificity
Neoplasms

Keywords

  • Breast cancer
  • DCIS
  • EIC
  • Intraductal spread
  • MRI

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Pharmacology (medical)

Cite this

Hiramatsu, H., Enomoto, K., Ikeda, T., Mukai, M., Furukawa, J., Kikuchi, K., ... Hiramatsu, K. (1997). The role of contrast-enhanced high resolution MRI in the surgical planning of breast cancer. Breast Cancer, 4(4), 285-290. https://doi.org/10.1007/BF02966523

The role of contrast-enhanced high resolution MRI in the surgical planning of breast cancer. / Hiramatsu, Hideko; Enomoto, Kohji; Ikeda, Tadashi; Mukai, Makio; Furukawa, Junji; Kikuchi, Kiyoshi; Oshio, Koichi; Hiraoka, Nobuyoshi; Kitajima, Masaki; Hiramatsu, Kyoichi.

In: Breast Cancer, Vol. 4, No. 4, 12.1997, p. 285-290.

Research output: Contribution to journalArticle

Hiramatsu, H, Enomoto, K, Ikeda, T, Mukai, M, Furukawa, J, Kikuchi, K, Oshio, K, Hiraoka, N, Kitajima, M & Hiramatsu, K 1997, 'The role of contrast-enhanced high resolution MRI in the surgical planning of breast cancer', Breast Cancer, vol. 4, no. 4, pp. 285-290. https://doi.org/10.1007/BF02966523
Hiramatsu H, Enomoto K, Ikeda T, Mukai M, Furukawa J, Kikuchi K et al. The role of contrast-enhanced high resolution MRI in the surgical planning of breast cancer. Breast Cancer. 1997 Dec;4(4):285-290. https://doi.org/10.1007/BF02966523
Hiramatsu, Hideko ; Enomoto, Kohji ; Ikeda, Tadashi ; Mukai, Makio ; Furukawa, Junji ; Kikuchi, Kiyoshi ; Oshio, Koichi ; Hiraoka, Nobuyoshi ; Kitajima, Masaki ; Hiramatsu, Kyoichi. / The role of contrast-enhanced high resolution MRI in the surgical planning of breast cancer. In: Breast Cancer. 1997 ; Vol. 4, No. 4. pp. 285-290.
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