The Role of Surgery in Advanced Neuroblastoma

J. Yokoyama, H. Ikawa, M. Endow, Y. Fuchimoto, K. Watanabe, R. Hosoya, K. Nishimura

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Recently we performed multi-modal therapy including chemotherapy with bone marrow transplantation (BMT), surgery, and local irradiation in the treatment of advanced neuroblastoma. As a result, all Stage III patients survived, and 4 out of 8 Stage IV patients who underwent our original systemic gross complete resection achieved long-term survival, 4y 8m, 5y 8m, 5y 6m and 5y 5m, respectively. Long-term survival patients were treated by local irradiation, brain surgery and intensive induction chemotherapy before primary site operation, and when resolution of distant metastases was obtained, the primary site was resected completely, followed by postoperative supralethal chemotherapy with BMT. The purpose of this report is to elucidate the role of surgery in advanced neuroblastoma based on our clinical results.

Original languageEnglish
Pages (from-to)23-26
Number of pages4
JournalEuropean Journal of Pediatric Surgery
Volume5
Issue number1
DOIs
Publication statusPublished - 1995 Feb

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Keywords

  • Bone marrow transplantation
  • Intensive chemotherapy
  • Neuroblastoma
  • Surgery

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery

Cite this

Yokoyama, J., Ikawa, H., Endow, M., Fuchimoto, Y., Watanabe, K., Hosoya, R., & Nishimura, K. (1995). The Role of Surgery in Advanced Neuroblastoma. European Journal of Pediatric Surgery, 5(1), 23-26. https://doi.org/10.1055/s-2008-1066156