The absolute configuration of the oxirane moiety in asperlin is shown to be (6S,7R) by an unambiguous synthesis of its (6R,7S)-diastereoisomer from D-glucose involving a tandem epoxide formation and intramolecular Wadsworth-Emmons-Horner olefination.
|Number of pages||2|
|Journal||Journal of the Chemical Society, Chemical Communications|
|Publication status||Published - 1988 Dec 1|
ASJC Scopus subject areas
- Molecular Medicine