The structures of citreohybridone A and B novel sesterterpenoid-type metabolites of a hybrid strain KO 0031 derived from penicillium citreo-viride B. IFO 6200 and 4692

Seiji Kosemura, Kimihiro Matsunaga, Shosuke Yamamura, Mari Kubota, Shigeru Ohba

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Two new cytotoxic substances against HeLa cell, citreohybridone A and B, have been isolated from the mycelium of a hybrid strain KO 0031 derived from Penicillium citreo-viride B.IFO 6200 and 4692, and their stereostructures have also been elucidated on the basis of their spectral data coupled with an X-ray crystallographic analysis of the citreohybridone A. These metabolites are regarded as new type of sesterterpenoids.

Original languageEnglish
Pages (from-to)3543-3546
Number of pages4
JournalTetrahedron Letters
Volume32
Issue number29
DOIs
Publication statusPublished - 1991 Jul 15

Fingerprint

Penicillium
Mycelium
Metabolites
HeLa Cells
X-Rays
X rays

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

The structures of citreohybridone A and B novel sesterterpenoid-type metabolites of a hybrid strain KO 0031 derived from penicillium citreo-viride B. IFO 6200 and 4692. / Kosemura, Seiji; Matsunaga, Kimihiro; Yamamura, Shosuke; Kubota, Mari; Ohba, Shigeru.

In: Tetrahedron Letters, Vol. 32, No. 29, 15.07.1991, p. 3543-3546.

Research output: Contribution to journalArticle

@article{fb6b469ed2064d7a99c2951c94096c93,
title = "The structures of citreohybridone A and B novel sesterterpenoid-type metabolites of a hybrid strain KO 0031 derived from penicillium citreo-viride B. IFO 6200 and 4692",
abstract = "Two new cytotoxic substances against HeLa cell, citreohybridone A and B, have been isolated from the mycelium of a hybrid strain KO 0031 derived from Penicillium citreo-viride B.IFO 6200 and 4692, and their stereostructures have also been elucidated on the basis of their spectral data coupled with an X-ray crystallographic analysis of the citreohybridone A. These metabolites are regarded as new type of sesterterpenoids.",
author = "Seiji Kosemura and Kimihiro Matsunaga and Shosuke Yamamura and Mari Kubota and Shigeru Ohba",
year = "1991",
month = "7",
day = "15",
doi = "10.1016/0040-4039(91)80828-T",
language = "English",
volume = "32",
pages = "3543--3546",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "29",

}

TY - JOUR

T1 - The structures of citreohybridone A and B novel sesterterpenoid-type metabolites of a hybrid strain KO 0031 derived from penicillium citreo-viride B. IFO 6200 and 4692

AU - Kosemura, Seiji

AU - Matsunaga, Kimihiro

AU - Yamamura, Shosuke

AU - Kubota, Mari

AU - Ohba, Shigeru

PY - 1991/7/15

Y1 - 1991/7/15

N2 - Two new cytotoxic substances against HeLa cell, citreohybridone A and B, have been isolated from the mycelium of a hybrid strain KO 0031 derived from Penicillium citreo-viride B.IFO 6200 and 4692, and their stereostructures have also been elucidated on the basis of their spectral data coupled with an X-ray crystallographic analysis of the citreohybridone A. These metabolites are regarded as new type of sesterterpenoids.

AB - Two new cytotoxic substances against HeLa cell, citreohybridone A and B, have been isolated from the mycelium of a hybrid strain KO 0031 derived from Penicillium citreo-viride B.IFO 6200 and 4692, and their stereostructures have also been elucidated on the basis of their spectral data coupled with an X-ray crystallographic analysis of the citreohybridone A. These metabolites are regarded as new type of sesterterpenoids.

UR - http://www.scopus.com/inward/record.url?scp=0025797047&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025797047&partnerID=8YFLogxK

U2 - 10.1016/0040-4039(91)80828-T

DO - 10.1016/0040-4039(91)80828-T

M3 - Article

AN - SCOPUS:0025797047

VL - 32

SP - 3543

EP - 3546

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 29

ER -