The structures of citreohybridone A and B novel sesterterpenoid-type metabolites of a hybrid strain KO 0031 derived from penicillium citreo-viride B. IFO 6200 and 4692

Seiji Kosemura, Kimihiro Matsunaga, Shosuke Yamamura, Mari Kubota, Shigeru Ohba

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Two new cytotoxic substances against HeLa cell, citreohybridone A and B, have been isolated from the mycelium of a hybrid strain KO 0031 derived from Penicillium citreo-viride B.IFO 6200 and 4692, and their stereostructures have also been elucidated on the basis of their spectral data coupled with an X-ray crystallographic analysis of the citreohybridone A. These metabolites are regarded as new type of sesterterpenoids.

Original languageEnglish
Pages (from-to)3543-3546
Number of pages4
JournalTetrahedron Letters
Volume32
Issue number29
DOIs
Publication statusPublished - 1991 Jul 15

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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