Two new cytotoxic substances against HeLa cell, citreohybridone A and B, have been isolated from the mycelium of a hybrid strain KO 0031 derived from Penicillium citreo-viride B.IFO 6200 and 4692, and their stereostructures have also been elucidated on the basis of their spectral data coupled with an X-ray crystallographic analysis of the citreohybridone A. These metabolites are regarded as new type of sesterterpenoids.
|Number of pages||4|
|Publication status||Published - 1991 Jul 15|
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry