Thermal decarboxylative Nazarov cyclization of cyclic enol carbonates involving chirality transfer

Akane Kozuma, Keiichi Komatsuki, Kodai Saito, Tohru Yamada

Research output: Contribution to journalArticle

Abstract

Decarboxylative Nazarov cyclization of chiral cyclic enol carbonates proceeded to afford chiral 2-cyclopentenones with excellent chirality transfer under thermal conditions without any catalyst. Interestingly, the thermal decarboxylative Nazarov cyclization furnished the desired product with better chirality transfer than the Lewis acid-catalyzed reaction.

Original languageEnglish
Pages (from-to)60-63
Number of pages4
JournalChemistry Letters
Volume49
Issue number1
DOIs
Publication statusPublished - 2020 Jan 1

Fingerprint

Chirality
Carbonates
Cyclization
Lewis Acids
Catalysts
Hot Temperature
cyclopentenone

Keywords

  • Chirality transfer
  • Decarboxylation
  • Electrocyclization

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Thermal decarboxylative Nazarov cyclization of cyclic enol carbonates involving chirality transfer. / Kozuma, Akane; Komatsuki, Keiichi; Saito, Kodai; Yamada, Tohru.

In: Chemistry Letters, Vol. 49, No. 1, 01.01.2020, p. 60-63.

Research output: Contribution to journalArticle

Kozuma, Akane ; Komatsuki, Keiichi ; Saito, Kodai ; Yamada, Tohru. / Thermal decarboxylative Nazarov cyclization of cyclic enol carbonates involving chirality transfer. In: Chemistry Letters. 2020 ; Vol. 49, No. 1. pp. 60-63.
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