Thermo-responsive protein adsorbing materials for purifying pharmaceutical protein on exposed charging surface

Kenichi Nagase, Simuck F. Yuk, Jun Kobayashi, Akihiko Kikuchi, Yoshikatsu Akiyama, Hideko Kanazawa, Teruo Okano

Research output: Contribution to journalArticle

37 Citations (Scopus)


Thermo-responsive anionic terpolymer brushes with high selectivity for proteins were prepared though surface-initiated ATRP. Utilizing these terpolymer brushes, pure lysozyme was successfully separated from egg-white. Thus, the prepared thermo-responsive terpolymer brush is an effective separation tool for the pharmaceutical and biotechnological industries that produce valuable proteins.

Original languageEnglish
Pages (from-to)2590-2593
Number of pages4
JournalJournal of Materials Chemistry
Issue number8
Publication statusPublished - 2011 Feb 28


ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Chemistry

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