Three-dimensional cardiac cine imaging using the kat ARC acceleration: Initial experience in clinical adult patients at 3T

Shigeo Okuda, Yoshitake Yamada, Akihiro Tanimoto, Jun Fujita, Motoaki Sano, Keiichi Fukuda, Sachio Kuribayashi, Masahiro Jinzaki, Atsushi Nozaki, Peng Lai

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3 Citations (Scopus)

Abstract

Objective: Three-dimensional cardiac cine imaging has demonstrated promising clinical 1.5-Tesla results; however, its application to 3. T scanners has been limited because of the higher sensitivity to off-resonance artifacts. The aim of this study was to apply 3D cardiac cine imaging during a single breath hold in clinical patients on a 3. T scanner using the kat ARC (k- and adaptive-t auto-calibrating reconstruction for Cartesian sampling) technique and to evaluate the interchangeability between 2D and 3D cine imaging for cardiac functional analysis and detection of abnormalities in regional wall motion. Methods: Following institutional review board approval, we obtained 2D cine images with an acceleration factor of two during multiple breath holds and 3D cine images with a net scan acceleration factor of 7.7 during a single breath hold in 20 patients using a 3. T unit. Two readers independently evaluated the wall motion of the left ventricle (LV) using a 5-point scale, and the consistency in the detection of regional wall motion abnormality between 2D and 3D cine was analyzed by Cohen's kappa test. The LV volume was calculated at end-diastole and end-systole (LVEDV, LVESV); the ejection fraction (LVEF) and myocardial weight (LVmass) were also calculated. The relationship between functional parameters calculated for 2D and 3D cine images was analyzed using Pearson's correlation analysis. The bias and 95% limit of agreement (LA) were calculated using Bland-Altman plots. In addition, a qualitative evaluation of image quality was performed with regard to the myocardium-blood contrast, noise level and boundary definition. Results: Despite slight degradation in image quality for 3D cine, excellent agreement was obtained for the detection of wall motion abnormalities between 2D and 3D cine images (κ. = 0.84 and 0.94 for each reader). Excellent correlations between the two imaging methods were shown for the evaluation of functional parameters (r. >. 0.97). Slight differences in LVEDV, LVESV, LVEF and LVmass were observed, with average values of 1.6. ±. 8.9. mL, - 0.6. ±. 5.9. mL, 1.4. ±. 3.6%, and 1.3. ±. 8.7. g, respectively. Conclusions: Images obtained using the kat ARC 3D and conventional 2D cine techniques were equivalent in the detection of regional wall motion abnormalities and the evaluation of cardiac functional parameters.

Original languageEnglish
JournalMagnetic Resonance Imaging
Volume33
Issue number7
DOIs
Publication statusPublished - 2015 Sep 1

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AIDS-Related Complex
Imaging techniques
Image quality
Heart Ventricles
Functional analysis
Diastole
Systole
Research Ethics Committees
Blood
Artifacts
Noise
Sampling
Myocardium
Degradation
Weights and Measures

Keywords

  • Cardiac imaging techniques
  • Cine
  • Magnetic resonance imaging
  • MRI at 3T
  • Three-dimensional

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging
  • Biomedical Engineering

Cite this

@article{962e5fdd856e49af82caee6b31b814a0,
title = "Three-dimensional cardiac cine imaging using the kat ARC acceleration: Initial experience in clinical adult patients at 3T",
abstract = "Objective: Three-dimensional cardiac cine imaging has demonstrated promising clinical 1.5-Tesla results; however, its application to 3. T scanners has been limited because of the higher sensitivity to off-resonance artifacts. The aim of this study was to apply 3D cardiac cine imaging during a single breath hold in clinical patients on a 3. T scanner using the kat ARC (k- and adaptive-t auto-calibrating reconstruction for Cartesian sampling) technique and to evaluate the interchangeability between 2D and 3D cine imaging for cardiac functional analysis and detection of abnormalities in regional wall motion. Methods: Following institutional review board approval, we obtained 2D cine images with an acceleration factor of two during multiple breath holds and 3D cine images with a net scan acceleration factor of 7.7 during a single breath hold in 20 patients using a 3. T unit. Two readers independently evaluated the wall motion of the left ventricle (LV) using a 5-point scale, and the consistency in the detection of regional wall motion abnormality between 2D and 3D cine was analyzed by Cohen's kappa test. The LV volume was calculated at end-diastole and end-systole (LVEDV, LVESV); the ejection fraction (LVEF) and myocardial weight (LVmass) were also calculated. The relationship between functional parameters calculated for 2D and 3D cine images was analyzed using Pearson's correlation analysis. The bias and 95{\%} limit of agreement (LA) were calculated using Bland-Altman plots. In addition, a qualitative evaluation of image quality was performed with regard to the myocardium-blood contrast, noise level and boundary definition. Results: Despite slight degradation in image quality for 3D cine, excellent agreement was obtained for the detection of wall motion abnormalities between 2D and 3D cine images (κ. = 0.84 and 0.94 for each reader). Excellent correlations between the two imaging methods were shown for the evaluation of functional parameters (r. >. 0.97). Slight differences in LVEDV, LVESV, LVEF and LVmass were observed, with average values of 1.6. ±. 8.9. mL, - 0.6. ±. 5.9. mL, 1.4. ±. 3.6{\%}, and 1.3. ±. 8.7. g, respectively. Conclusions: Images obtained using the kat ARC 3D and conventional 2D cine techniques were equivalent in the detection of regional wall motion abnormalities and the evaluation of cardiac functional parameters.",
keywords = "Cardiac imaging techniques, Cine, Magnetic resonance imaging, MRI at 3T, Three-dimensional",
author = "Shigeo Okuda and Yoshitake Yamada and Akihiro Tanimoto and Jun Fujita and Motoaki Sano and Keiichi Fukuda and Sachio Kuribayashi and Masahiro Jinzaki and Atsushi Nozaki and Peng Lai",
year = "2015",
month = "9",
day = "1",
doi = "10.1016/j.mri.2015.04.004",
language = "English",
volume = "33",
journal = "Magnetic Resonance Imaging",
issn = "0730-725X",
publisher = "Elsevier Inc.",
number = "7",

}

TY - JOUR

T1 - Three-dimensional cardiac cine imaging using the kat ARC acceleration

T2 - Initial experience in clinical adult patients at 3T

AU - Okuda, Shigeo

AU - Yamada, Yoshitake

AU - Tanimoto, Akihiro

AU - Fujita, Jun

AU - Sano, Motoaki

AU - Fukuda, Keiichi

AU - Kuribayashi, Sachio

AU - Jinzaki, Masahiro

AU - Nozaki, Atsushi

AU - Lai, Peng

PY - 2015/9/1

Y1 - 2015/9/1

N2 - Objective: Three-dimensional cardiac cine imaging has demonstrated promising clinical 1.5-Tesla results; however, its application to 3. T scanners has been limited because of the higher sensitivity to off-resonance artifacts. The aim of this study was to apply 3D cardiac cine imaging during a single breath hold in clinical patients on a 3. T scanner using the kat ARC (k- and adaptive-t auto-calibrating reconstruction for Cartesian sampling) technique and to evaluate the interchangeability between 2D and 3D cine imaging for cardiac functional analysis and detection of abnormalities in regional wall motion. Methods: Following institutional review board approval, we obtained 2D cine images with an acceleration factor of two during multiple breath holds and 3D cine images with a net scan acceleration factor of 7.7 during a single breath hold in 20 patients using a 3. T unit. Two readers independently evaluated the wall motion of the left ventricle (LV) using a 5-point scale, and the consistency in the detection of regional wall motion abnormality between 2D and 3D cine was analyzed by Cohen's kappa test. The LV volume was calculated at end-diastole and end-systole (LVEDV, LVESV); the ejection fraction (LVEF) and myocardial weight (LVmass) were also calculated. The relationship between functional parameters calculated for 2D and 3D cine images was analyzed using Pearson's correlation analysis. The bias and 95% limit of agreement (LA) were calculated using Bland-Altman plots. In addition, a qualitative evaluation of image quality was performed with regard to the myocardium-blood contrast, noise level and boundary definition. Results: Despite slight degradation in image quality for 3D cine, excellent agreement was obtained for the detection of wall motion abnormalities between 2D and 3D cine images (κ. = 0.84 and 0.94 for each reader). Excellent correlations between the two imaging methods were shown for the evaluation of functional parameters (r. >. 0.97). Slight differences in LVEDV, LVESV, LVEF and LVmass were observed, with average values of 1.6. ±. 8.9. mL, - 0.6. ±. 5.9. mL, 1.4. ±. 3.6%, and 1.3. ±. 8.7. g, respectively. Conclusions: Images obtained using the kat ARC 3D and conventional 2D cine techniques were equivalent in the detection of regional wall motion abnormalities and the evaluation of cardiac functional parameters.

AB - Objective: Three-dimensional cardiac cine imaging has demonstrated promising clinical 1.5-Tesla results; however, its application to 3. T scanners has been limited because of the higher sensitivity to off-resonance artifacts. The aim of this study was to apply 3D cardiac cine imaging during a single breath hold in clinical patients on a 3. T scanner using the kat ARC (k- and adaptive-t auto-calibrating reconstruction for Cartesian sampling) technique and to evaluate the interchangeability between 2D and 3D cine imaging for cardiac functional analysis and detection of abnormalities in regional wall motion. Methods: Following institutional review board approval, we obtained 2D cine images with an acceleration factor of two during multiple breath holds and 3D cine images with a net scan acceleration factor of 7.7 during a single breath hold in 20 patients using a 3. T unit. Two readers independently evaluated the wall motion of the left ventricle (LV) using a 5-point scale, and the consistency in the detection of regional wall motion abnormality between 2D and 3D cine was analyzed by Cohen's kappa test. The LV volume was calculated at end-diastole and end-systole (LVEDV, LVESV); the ejection fraction (LVEF) and myocardial weight (LVmass) were also calculated. The relationship between functional parameters calculated for 2D and 3D cine images was analyzed using Pearson's correlation analysis. The bias and 95% limit of agreement (LA) were calculated using Bland-Altman plots. In addition, a qualitative evaluation of image quality was performed with regard to the myocardium-blood contrast, noise level and boundary definition. Results: Despite slight degradation in image quality for 3D cine, excellent agreement was obtained for the detection of wall motion abnormalities between 2D and 3D cine images (κ. = 0.84 and 0.94 for each reader). Excellent correlations between the two imaging methods were shown for the evaluation of functional parameters (r. >. 0.97). Slight differences in LVEDV, LVESV, LVEF and LVmass were observed, with average values of 1.6. ±. 8.9. mL, - 0.6. ±. 5.9. mL, 1.4. ±. 3.6%, and 1.3. ±. 8.7. g, respectively. Conclusions: Images obtained using the kat ARC 3D and conventional 2D cine techniques were equivalent in the detection of regional wall motion abnormalities and the evaluation of cardiac functional parameters.

KW - Cardiac imaging techniques

KW - Cine

KW - Magnetic resonance imaging

KW - MRI at 3T

KW - Three-dimensional

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DO - 10.1016/j.mri.2015.04.004

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JO - Magnetic Resonance Imaging

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