Three-dimensional imaging and mapping of the right and left phrenic nerves: Relevance to interventional cardiovascular therapy

Kotaro Fukumoto, Seiji Takatsuki, Masahiro Jinzaki, Minoru Yamada, Kojiro Tanimoto, Nobuhiro Nishiyama, Yoshiyasu Aizawa, Yoko Hagiwara, Yukiko Fukuda, Takehiro Kimura, Shunichiro Miyoshi, Sachio Kuribayashi, Keiichi Fukuda

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9 Citations (Scopus)

Abstract

AimsPhrenic nerves (PNs) can be damaged during interventional cardiovascular therapy because of the nerves' proximity to the heart. This study aimed to analyse the anatomy of the PN by performing three-dimensional (3-D) imaging and pace mapping.Methods and resultsForty consecutive patients with atrial fibrillation referred for catheter ablation were enrolled in this study and underwent preoperative cardiovascular computed tomography (CT). In 10 patients with sinus rhythm during tomography, 3-D images of the right and left pericardiophrenic bundles (PBs), consisting of the ipsilateral PN and accompanying vessels, were reconstructed from the CT data. During the electrophysiological study, PN pace mapping was performed from both atria. The course of the PBs generated by CT imaging and the PN pace map generated by the 3-D mapping system were compared. By electrical pacing, the PNs were captured in 40 individuals (100%) from the superior vena cava and the right atrium, and in 17 patients (43%) from the left atrial appendage. Clear 3-D images of PBs were reconstructed in all cases in which CT-reconstruction was performed. The distance between the locations of the right PB generated by CT imaging and those of the right PN-capture sites in the right-sided heart on the mapping system was 8.7 ± 5.8 mm.ConclusionsThe 3-D routes of the bilateral PNs passing near the heart were verified by pace mapping. The preoperatively reconstructed 3-D course of the PB succeeded in locating the PN, which may facilitate the comprehension of PN anatomy to avoid its injury during interventional cardiovascular therapy.

Original languageEnglish
Pages (from-to)937-943
Number of pages7
JournalEuropace
Volume15
Issue number7
DOIs
Publication statusPublished - 2013 Jul 1

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Keywords

  • Atrial fibrillation
  • Catheter ablation
  • Computed tomography
  • Open chest surgery
  • Phrenic nerve

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Cite this

Fukumoto, K., Takatsuki, S., Jinzaki, M., Yamada, M., Tanimoto, K., Nishiyama, N., Aizawa, Y., Hagiwara, Y., Fukuda, Y., Kimura, T., Miyoshi, S., Kuribayashi, S., & Fukuda, K. (2013). Three-dimensional imaging and mapping of the right and left phrenic nerves: Relevance to interventional cardiovascular therapy. Europace, 15(7), 937-943. https://doi.org/10.1093/europace/eus439