Three-dimensional visualization of hypoxia-induced pulmonary vascular remodeling in mice

Takayuki Fujiwara; Norifumi Takeda; Hironori Hara; Satoshi Ishii; Genri Numata; Hiroyuki Tokiwa; Sonoko Maemura; Takaaki Suzuki; Hiroshi Takiguchi; Yoshiaki Kubota; Kinya Seo; Asuka Sakata; Seitaro Nomura; Masaru Hatano; Kazutaka Ueda; Mutsuo Harada; Haruhiro Toko; Eiki Takimoto; Hiroshi Akazawa; Satoshi Nishimura; Issei Komuro

doi:10.1161/CIRCULATIONAHA.121.056219

Three-dimensional visualization of hypoxia-induced pulmonary vascular remodeling in mice

Takayuki Fujiwara, Norifumi Takeda, Hironori Hara, Satoshi Ishii, Genri Numata, Hiroyuki Tokiwa, Sonoko Maemura, Takaaki Suzuki, Hiroshi Takiguchi, Yoshiaki Kubota, Kinya Seo, Asuka Sakata, Seitaro Nomura, Masaru Hatano, Kazutaka Ueda, Mutsuo Harada, Haruhiro Toko, Eiki Takimoto, Hiroshi Akazawa, Satoshi NishimuraIssei Komuro

Department of Anatomy

Research output: Contribution to journal › Letter › peer-review

2 Citations (Scopus)

Original language	English
Pages (from-to)	1452-1455
Number of pages	4
Journal	Circulation
DOIs	https://doi.org/10.1161/CIRCULATIONAHA.121.056219
Publication status	Accepted/In press - 2021

Keywords

Endothelial cells
Microscopy, fluorescence, multiphoton
Myocytes, smooth muscle
Neovascularization, pathologic

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Physiology (medical)

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10.1161/CIRCULATIONAHA.121.056219

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Fujiwara, T., Takeda, N., Hara, H., Ishii, S., Numata, G., Tokiwa, H., Maemura, S., Suzuki, T., Takiguchi, H., Kubota, Y., Seo, K., Sakata, A., Nomura, S., Hatano, M., Ueda, K., Harada, M., Toko, H., Takimoto, E., Akazawa, H., ... Komuro, I. (Accepted/In press). Three-dimensional visualization of hypoxia-induced pulmonary vascular remodeling in mice. Circulation, 1452-1455. https://doi.org/10.1161/CIRCULATIONAHA.121.056219

Fujiwara, T, Takeda, N, Hara, H, Ishii, S, Numata, G, Tokiwa, H, Maemura, S, Suzuki, T, Takiguchi, H, Kubota, Y, Seo, K, Sakata, A, Nomura, S, Hatano, M, Ueda, K, Harada, M, Toko, H, Takimoto, E, Akazawa, H, Nishimura, S & Komuro, I 2021, 'Three-dimensional visualization of hypoxia-induced pulmonary vascular remodeling in mice', Circulation, pp. 1452-1455. https://doi.org/10.1161/CIRCULATIONAHA.121.056219

@article{f1bb10bd07234b5a9f8c9c2d3afbbda5,

title = "Three-dimensional visualization of hypoxia-induced pulmonary vascular remodeling in mice",

keywords = "Endothelial cells, Microscopy, fluorescence, multiphoton, Myocytes, smooth muscle, Neovascularization, pathologic",

author = "Takayuki Fujiwara and Norifumi Takeda and Hironori Hara and Satoshi Ishii and Genri Numata and Hiroyuki Tokiwa and Sonoko Maemura and Takaaki Suzuki and Hiroshi Takiguchi and Yoshiaki Kubota and Kinya Seo and Asuka Sakata and Seitaro Nomura and Masaru Hatano and Kazutaka Ueda and Mutsuo Harada and Haruhiro Toko and Eiki Takimoto and Hiroshi Akazawa and Satoshi Nishimura and Issei Komuro",

note = "Funding Information: This work was supported by the Practical Research Project for Rare/Intractable Diseases from Japan Agency for Medical Research and Development (grants 20ek0109487h0001 to Drs Fujiwara, Takeda, and Komuro and 21ek0109560h0001 to Drs Fujiwara and Takeda), grants-in-aid for Scientific Research from the Japan Society for the Promotion of Science (to Dr Fujiwara), MSD Life Science Foundation (to Drs Fujiwara and Takeda), SENSIN Medical Research Foundation (to Dr Takeda), Novaltis Pharma Grants for Basic Research (to Dr Takeda), Bristol-Meyers Squibb Foundation (to Dr Takeda), and Nippon Shinyaku Co, Ltd (to Dr Fujiwara). ",

year = "2021",

doi = "10.1161/CIRCULATIONAHA.121.056219",

language = "English",

pages = "1452--1455",

journal = "Circulation",

issn = "0009-7322",

publisher = "Lippincott Williams and Wilkins",

}

TY - JOUR

T1 - Three-dimensional visualization of hypoxia-induced pulmonary vascular remodeling in mice

AU - Fujiwara, Takayuki

AU - Takeda, Norifumi

AU - Hara, Hironori

AU - Ishii, Satoshi

AU - Numata, Genri

AU - Tokiwa, Hiroyuki

AU - Maemura, Sonoko

AU - Suzuki, Takaaki

AU - Takiguchi, Hiroshi

AU - Kubota, Yoshiaki

AU - Seo, Kinya

AU - Sakata, Asuka

AU - Nomura, Seitaro

AU - Hatano, Masaru

AU - Ueda, Kazutaka

AU - Harada, Mutsuo

AU - Toko, Haruhiro

AU - Takimoto, Eiki

AU - Akazawa, Hiroshi

AU - Nishimura, Satoshi

AU - Komuro, Issei

N1 - Funding Information: This work was supported by the Practical Research Project for Rare/Intractable Diseases from Japan Agency for Medical Research and Development (grants 20ek0109487h0001 to Drs Fujiwara, Takeda, and Komuro and 21ek0109560h0001 to Drs Fujiwara and Takeda), grants-in-aid for Scientific Research from the Japan Society for the Promotion of Science (to Dr Fujiwara), MSD Life Science Foundation (to Drs Fujiwara and Takeda), SENSIN Medical Research Foundation (to Dr Takeda), Novaltis Pharma Grants for Basic Research (to Dr Takeda), Bristol-Meyers Squibb Foundation (to Dr Takeda), and Nippon Shinyaku Co, Ltd (to Dr Fujiwara).

PY - 2021

Y1 - 2021

KW - Endothelial cells

KW - Microscopy, fluorescence, multiphoton

KW - Myocytes, smooth muscle

KW - Neovascularization, pathologic

UR - http://www.scopus.com/inward/record.url?scp=85118640430&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85118640430&partnerID=8YFLogxK

U2 - 10.1161/CIRCULATIONAHA.121.056219

DO - 10.1161/CIRCULATIONAHA.121.056219

M3 - Letter

C2 - 34694894

AN - SCOPUS:85118640430

SN - 0009-7322

SP - 1452

EP - 1455

JO - Circulation

JF - Circulation

ER -

Three-dimensional visualization of hypoxia-induced pulmonary vascular remodeling in mice

Keywords

ASJC Scopus subject areas

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