Three new nardosinane type sesquiterpenes from an Indonesian soft coral Nephthea sp.

Magie Melanie Kapojos; Remy Emile Petrus Mangindaan; Takahiro Nakazawa; Taiko Oda; Kazuyo Ukai; Michio Namikoshi

doi:10.1248/cpb.56.332

Three new nardosinane type sesquiterpenes from an Indonesian soft coral Nephthea sp.

Magie Melanie Kapojos, Remy Emile Petrus Mangindaan, Takahiro Nakazawa, Taiko Oda, Kazuyo Ukai, Michio Namikoshi

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

Three new sesquiterpenes, 2-deoxy-7-O-methyllemnacarnol (1), 2-deoxy-12α-ethoxy-7-O-methyllemnacarnol (2), and 2-deoxy-12α- methoxy-7-O-methyllemnacarnol (3), were isolated from a soft coral Nephthea sp. collected in Indonesia, together with five known sesquiterpenes. The structures of the new compounds were assigned on the basis of their spectroscopic data.

Original language	English
Pages (from-to)	332-334
Number of pages	3
Journal	Chemical and Pharmaceutical Bulletin
Volume	56
Issue number	3
DOIs	https://doi.org/10.1248/cpb.56.332
Publication status	Published - 2008 Mar

Keywords

Lemnacarnol derivative
Nephthea sp.
Sesquiterpene
Soft coral

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

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10.1248/cpb.56.332

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abstract = "Three new sesquiterpenes, 2-deoxy-7-O-methyllemnacarnol (1), 2-deoxy-12α-ethoxy-7-O-methyllemnacarnol (2), and 2-deoxy-12α- methoxy-7-O-methyllemnacarnol (3), were isolated from a soft coral Nephthea sp. collected in Indonesia, together with five known sesquiterpenes. The structures of the new compounds were assigned on the basis of their spectroscopic data.",

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AU - Oda, Taiko

AU - Ukai, Kazuyo

AU - Namikoshi, Michio

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AB - Three new sesquiterpenes, 2-deoxy-7-O-methyllemnacarnol (1), 2-deoxy-12α-ethoxy-7-O-methyllemnacarnol (2), and 2-deoxy-12α- methoxy-7-O-methyllemnacarnol (3), were isolated from a soft coral Nephthea sp. collected in Indonesia, together with five known sesquiterpenes. The structures of the new compounds were assigned on the basis of their spectroscopic data.

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