Thrombocytopenia responsive to warfarin in a patient with systemic sclerosis-systemic lupus erythematosus overlap

M. Kuwana, J. Kaburaki, M. Hirakata, T. Tojo, M. Handa, Y. Ikeda

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

We report a patient with overlapping systemic sclerosis-systemic lupus erythematosus who developed refractory thrombocytopenia and recurrent thromboses. Coagulation and platelet labeling studies revealed that platelets were being consumed by the thrombus formation, and anticoagulation with warfarin dramatically increased the platelet count. This case report suggests that platelet consumption due to thrombus formation is one of the causes of thrombocytopenia in patients with rheumatic disease.

Original languageEnglish
Pages (from-to)103-106
Number of pages4
JournalClinical and experimental rheumatology
Volume13
Issue number1
Publication statusPublished - 1995 Jan 1

Keywords

  • systemic lupus erythematosus
  • systemic sclerosis
  • thrombocytopenia
  • thrombosis
  • von Willebrand factor

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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