Thymoma-associated T-cell immunodeficiency after radiotherapy: A case report

Kensuke Nakagawara, Shotaro Chubachi, Shuhei Azekawa, Shiro Otake, Ayaka Saito, Masahiko Okada, Ko Lee, Katsunori Masaki, Naoyoshi Koike, Hirofumi Kamata, Ichiro Kawada, Shigeaki Suzuki, Makoto Ishii, Koichi Fukunaga

Research output: Contribution to journalArticlepeer-review

Abstract

Acquired immunodeficiency in thymoma (Good's syndrome) without hypogammaglobulinemia is a rare condition. Here we describe the case of a 29-year-old Japanese woman with thymoma-associated T cell immunodeficiency after radiation therapy. She was admitted to the hospital with refractory pneumonia, which resulted from as T cell immunodeficiency, as revealed through low peripheral lymphocytes and oral candidiasis triggered through radiotherapy and required long-term antimicrobial therapy. Although radiotherapy is commonly administered for thymoma, our findings suggest that physicians should consider carrying out lymphocyte counts during thymoma treatment.

Original languageEnglish
Article number101408
JournalRespiratory Medicine Case Reports
Volume33
DOIs
Publication statusPublished - 2021 Jan

Keywords

  • Myasthenia gravis
  • Oral candidiasis
  • Pneumoniae
  • Radiotherapy
  • T-cell immunodeficiency
  • Thymoma

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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