Time-resolved spatial sensitivity profiles on the surface of brain cortex

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

The time-resolved spatial sensitivity profiles on the brain surface and in the plane perpendicular to the brain surface are predicted by Monte Carlo simulation to discuss the volume of tissue sampled by multi-channel near infrared instruments. The adult head model consists of five types of tissue. The temporal point spread function of the detected light is divided into five parts and the trajectories of photons detected during each gate are accumulated to obtain the time-resolved spatial sensitivity profiles. Early photons only graze the cortex surface around the middle of the source and detector whilst late photons tend to penetrate into white matter. The spatial sensitivity profiles for the late photons widely spread on the cortex surface. These results suggest that the detected signal mainly reflects the absorption change in the grey matter.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsS. Andersson-Engels, M.F. Kaschke
Pages219-225
Number of pages7
Volume4431
DOIs
Publication statusPublished - 2001
EventPhoton Migration, Optical Coherence Tomography, and Microscopy - Munich, Germany
Duration: 2001 Jun 182001 Jun 21

Other

OtherPhoton Migration, Optical Coherence Tomography, and Microscopy
CountryGermany
CityMunich
Period01/6/1801/6/21

Fingerprint

cortexes
brain
Brain
Photons
sensitivity
photons
profiles
Infrared instruments
Tissue
infrared instruments
Optical transfer function
point spread functions
Light sources
Trajectories
trajectories
Detectors
detectors
simulation

Keywords

  • Monte Carlo simulation
  • Multi-channel near infrared instrument
  • Time-resolved measurement

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Okada, E. (2001). Time-resolved spatial sensitivity profiles on the surface of brain cortex. In S. Andersson-Engels, & M. F. Kaschke (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 4431, pp. 219-225) https://doi.org/10.1117/12.447425

Time-resolved spatial sensitivity profiles on the surface of brain cortex. / Okada, Eiji.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / S. Andersson-Engels; M.F. Kaschke. Vol. 4431 2001. p. 219-225.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Okada, E 2001, Time-resolved spatial sensitivity profiles on the surface of brain cortex. in S Andersson-Engels & MF Kaschke (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 4431, pp. 219-225, Photon Migration, Optical Coherence Tomography, and Microscopy, Munich, Germany, 01/6/18. https://doi.org/10.1117/12.447425
Okada E. Time-resolved spatial sensitivity profiles on the surface of brain cortex. In Andersson-Engels S, Kaschke MF, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 4431. 2001. p. 219-225 https://doi.org/10.1117/12.447425
Okada, Eiji. / Time-resolved spatial sensitivity profiles on the surface of brain cortex. Proceedings of SPIE - The International Society for Optical Engineering. editor / S. Andersson-Engels ; M.F. Kaschke. Vol. 4431 2001. pp. 219-225
@inproceedings{a7f0b73f9a3540589940b1caaa3ffb4f,
title = "Time-resolved spatial sensitivity profiles on the surface of brain cortex",
abstract = "The time-resolved spatial sensitivity profiles on the brain surface and in the plane perpendicular to the brain surface are predicted by Monte Carlo simulation to discuss the volume of tissue sampled by multi-channel near infrared instruments. The adult head model consists of five types of tissue. The temporal point spread function of the detected light is divided into five parts and the trajectories of photons detected during each gate are accumulated to obtain the time-resolved spatial sensitivity profiles. Early photons only graze the cortex surface around the middle of the source and detector whilst late photons tend to penetrate into white matter. The spatial sensitivity profiles for the late photons widely spread on the cortex surface. These results suggest that the detected signal mainly reflects the absorption change in the grey matter.",
keywords = "Monte Carlo simulation, Multi-channel near infrared instrument, Time-resolved measurement",
author = "Eiji Okada",
year = "2001",
doi = "10.1117/12.447425",
language = "English",
volume = "4431",
pages = "219--225",
editor = "S. Andersson-Engels and M.F. Kaschke",
booktitle = "Proceedings of SPIE - The International Society for Optical Engineering",

}

TY - GEN

T1 - Time-resolved spatial sensitivity profiles on the surface of brain cortex

AU - Okada, Eiji

PY - 2001

Y1 - 2001

N2 - The time-resolved spatial sensitivity profiles on the brain surface and in the plane perpendicular to the brain surface are predicted by Monte Carlo simulation to discuss the volume of tissue sampled by multi-channel near infrared instruments. The adult head model consists of five types of tissue. The temporal point spread function of the detected light is divided into five parts and the trajectories of photons detected during each gate are accumulated to obtain the time-resolved spatial sensitivity profiles. Early photons only graze the cortex surface around the middle of the source and detector whilst late photons tend to penetrate into white matter. The spatial sensitivity profiles for the late photons widely spread on the cortex surface. These results suggest that the detected signal mainly reflects the absorption change in the grey matter.

AB - The time-resolved spatial sensitivity profiles on the brain surface and in the plane perpendicular to the brain surface are predicted by Monte Carlo simulation to discuss the volume of tissue sampled by multi-channel near infrared instruments. The adult head model consists of five types of tissue. The temporal point spread function of the detected light is divided into five parts and the trajectories of photons detected during each gate are accumulated to obtain the time-resolved spatial sensitivity profiles. Early photons only graze the cortex surface around the middle of the source and detector whilst late photons tend to penetrate into white matter. The spatial sensitivity profiles for the late photons widely spread on the cortex surface. These results suggest that the detected signal mainly reflects the absorption change in the grey matter.

KW - Monte Carlo simulation

KW - Multi-channel near infrared instrument

KW - Time-resolved measurement

UR - http://www.scopus.com/inward/record.url?scp=0035759898&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035759898&partnerID=8YFLogxK

U2 - 10.1117/12.447425

DO - 10.1117/12.447425

M3 - Conference contribution

VL - 4431

SP - 219

EP - 225

BT - Proceedings of SPIE - The International Society for Optical Engineering

A2 - Andersson-Engels, S.

A2 - Kaschke, M.F.

ER -