tincar encodes a novel transmembrane protein expressed in the Tinman-expressing cardioblasts of Drosophila

Yuki Hirota, Kazunobu Sawamoto, Hideyuki Okano

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1 Citation (Scopus)


We cloned and characterized the Drosophila gene, tincar (tinc), which encodes a novel protein with eight putative transmembrane domains. The tinc mRNA was expressed specifically in four of the six pairs of cardioblasts in each segment, in a pattern identical to that of tinman (tin), a homeobox gene required for the specification of the dorsal vessel. In the non-Tin-expressing pairs of cardioblasts, tinc transcription seemed to be repressed by Seven-up.

Original languageEnglish
Pages (from-to)323-327
Number of pages5
JournalGene Expression Patterns
Issue number3-4
Publication statusPublished - 2002 Dec 1



  • Cardioblast
  • Dorsal vessel
  • Drosophila
  • Heart
  • tincar
  • tinman

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Developmental Biology

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