tincar encodes a novel transmembrane protein expressed in the Tinman-expressing cardioblasts of Drosophila

Yuki Hirota, Kazunobu Sawamoto, Hideyuki Okano

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We cloned and characterized the Drosophila gene, tincar (tinc), which encodes a novel protein with eight putative transmembrane domains. The tinc mRNA was expressed specifically in four of the six pairs of cardioblasts in each segment, in a pattern identical to that of tinman (tin), a homeobox gene required for the specification of the dorsal vessel. In the non-Tin-expressing pairs of cardioblasts, tinc transcription seemed to be repressed by Seven-up.

Original languageEnglish
JournalMechanisms of Development
Volume119
Issue numberSUPPL. 1
DOIs
Publication statusPublished - 2002 Dec

Fingerprint

Homeobox Genes
Drosophila
Messenger RNA
Genes
Proteins

Keywords

  • Cardioblast
  • Dorsal vessel
  • Drosophila
  • Heart
  • tincar
  • tinman

ASJC Scopus subject areas

  • Developmental Biology
  • Developmental Neuroscience

Cite this

tincar encodes a novel transmembrane protein expressed in the Tinman-expressing cardioblasts of Drosophila. / Hirota, Yuki; Sawamoto, Kazunobu; Okano, Hideyuki.

In: Mechanisms of Development, Vol. 119, No. SUPPL. 1, 12.2002.

Research output: Contribution to journalArticle

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