Tissue engineering of the cornea

May Griffith, Fengfu Li, Chris Lohmann, Heather D. Sheardown, Shigeto Shimmura, David J. Carlsson

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Abstract

Over the years, there have been reports of tissue engineered (TE) corneas that range in complexity and functionality from materials and devices that are designed to restore solely the ocular function, to those that are designed to do this by integration with part or the full thickness of damaged or diseased corneas and promoting regeneration of the host tissue. TE lenticules are also being designed to be implanted into the cornea in order to alter the refractive properties of the eye, thereby improving vision. Beyond the need for vision restoration, there are other critical questions of bonding or integration with the host tissue and epithelial overgrowth to restore the cornea’s protective surface layer. Even more demanding, but very desirable, is the regeneration of innervation to restore touch and hydration sensitivity.

Original languageEnglish
Title of host publicationScaffolding in Tissue Engineering
PublisherCRC Press
Pages413-424
Number of pages12
ISBN (Electronic)9781420027563
ISBN (Print)9781574445213
Publication statusPublished - 2005 Jan 1
Externally publishedYes

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ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Engineering(all)
  • Materials Science(all)

Cite this

Griffith, M., Li, F., Lohmann, C., Sheardown, H. D., Shimmura, S., & Carlsson, D. J. (2005). Tissue engineering of the cornea. In Scaffolding in Tissue Engineering (pp. 413-424). CRC Press.