To test glutamate hypothesis for schizophrenia utilizing proton magnetic resonance spectroscopy

Sachiko Tsugawa, Shinichiro Nakajima

Research output: Contribution to journalReview article

Abstract

Recent advancement in magnetic resonance spectroscopy (MRS) has elucidated the pathophysiology of mental illness, including schizophrenia. MRS is a neuroimaging technique that non-invasively measures chemicals, using nuclear magnetic resonance. This narrative review explains proton MRS (1H-MRS) and introduces pivotal studies to examine a glutamate hypothesis for schizophrenia, employing 1H-MRS.

Original languageEnglish
Pages (from-to)1035-1040
Number of pages6
JournalBrain and Nerve
Volume69
Issue number9
Publication statusPublished - 2017 Sep 1

Keywords

  • Glutamate hypothesis
  • Magnetic resonance spectroscopy
  • Schizophrenia

ASJC Scopus subject areas

  • Clinical Neurology

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