Tokyo centenarian study 5 nutritional status of Japanese centenarians

N. Hirose, Yasumichi Arai, M. Kawamura, S. Homma, H. Hasegawa, Hiroyuki Ishida, K. Shimizu, Y. Osono, S. Takeda, H. Noji, A. Homma, Y. Nakamura

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

To establish the guideline for nutrition in the very old, we analyzed biochemical and hematological data from 45 Japanese centenarians living in Tokyo metropolitan area during 1994 and 1995. Levels of cholesterol, HDL- cholesterol, apolipoprotein A1 and B, albumin, prealbumin in serum were lower than in a control group or lower than the reference range, which indicates that these centenarians were undernourished. RBC counts, hemoglobin, and hematocrit were also low in the centenarians. The concentration of albumin correlated positively with those of HDL-cholesterol and apolipoprotein A1, and negatively with concentration of Lp(a). The value for transferrin correlated positively with energy intake and with the concentration of apolipoprotein A1. The concentration of prealbumin correlated positively with the concentration of hemoglobin, hematocrit and the total cholesterol concentration. According to their nutritional status, the centenarians were divided into 2 groups: wellnourished and undernourished. Those who were wellnourished had higher levels of cholesterol, HDL, Hb, and apolipoprotein A1, their levels of ADL and cognitive function were also high. The findings of blood-chemical data in the centenarians may be partly due to undernutrition. Centenarians who were wellnourished were considered to be aging successfully. These results and others previously published indicate that the concentrations of albumin, prealbumin, transferrin and either CRP or IL-6 are useful for nutritional assessment in the very old.

Original languageEnglish
Pages (from-to)324-330
Number of pages7
JournalJapanese Journal of Geriatrics
Volume34
Issue number4
Publication statusPublished - 1997
Externally publishedYes

Fingerprint

Tokyo
Nutritional Status
Apolipoprotein A-I
Prealbumin
Albumins
Transferrin
Hematocrit
HDL Cholesterol
Hemoglobins
Cholesterol
Nutrition Policy
Nutrition Assessment
Glycosylated Hemoglobin A
Apolipoproteins B
Activities of Daily Living
Hypercholesterolemia
Energy Intake
Malnutrition
Cognition
Interleukin-6

Keywords

  • Albumin
  • Centenarian
  • Nutritional parameter
  • Prealbumin
  • Transferrin
  • Undernourished

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Hirose, N., Arai, Y., Kawamura, M., Homma, S., Hasegawa, H., Ishida, H., ... Nakamura, Y. (1997). Tokyo centenarian study 5 nutritional status of Japanese centenarians. Japanese Journal of Geriatrics, 34(4), 324-330.

Tokyo centenarian study 5 nutritional status of Japanese centenarians. / Hirose, N.; Arai, Yasumichi; Kawamura, M.; Homma, S.; Hasegawa, H.; Ishida, Hiroyuki; Shimizu, K.; Osono, Y.; Takeda, S.; Noji, H.; Homma, A.; Nakamura, Y.

In: Japanese Journal of Geriatrics, Vol. 34, No. 4, 1997, p. 324-330.

Research output: Contribution to journalArticle

Hirose, N, Arai, Y, Kawamura, M, Homma, S, Hasegawa, H, Ishida, H, Shimizu, K, Osono, Y, Takeda, S, Noji, H, Homma, A & Nakamura, Y 1997, 'Tokyo centenarian study 5 nutritional status of Japanese centenarians', Japanese Journal of Geriatrics, vol. 34, no. 4, pp. 324-330.
Hirose, N. ; Arai, Yasumichi ; Kawamura, M. ; Homma, S. ; Hasegawa, H. ; Ishida, Hiroyuki ; Shimizu, K. ; Osono, Y. ; Takeda, S. ; Noji, H. ; Homma, A. ; Nakamura, Y. / Tokyo centenarian study 5 nutritional status of Japanese centenarians. In: Japanese Journal of Geriatrics. 1997 ; Vol. 34, No. 4. pp. 324-330.
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