Total syntheses of isodihydrofutoquinol a, futoquinol, and isofutoquinol A and B

Yoshikazu Shizuri, Kensuke Nakamura, Shosuke Yamamura, Shigeru Ohba, Hiroshi Yamashita, Yoshihiko Saito

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Isodihydrofutoquinol A has been synthesized starting from 4-benzyloxy-2-methoxy-acetophenone, wherein the 2,5-cyclohexadienone moiety has been constructed efficiently by means of electrochemical method. Isodihydrofutoquinol A has been further converted into isofutoquinol A and B through futoquinol. In addition, the stereostructure of isofutoquinol A has been unambiguously determined on the basis of an X-ray crystallographic analysis.

Original languageEnglish
Pages (from-to)727-730
Number of pages4
JournalTetrahedron Letters
Volume27
Issue number6
DOIs
Publication statusPublished - 1986

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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    Shizuri, Y., Nakamura, K., Yamamura, S., Ohba, S., Yamashita, H., & Saito, Y. (1986). Total syntheses of isodihydrofutoquinol a, futoquinol, and isofutoquinol A and B. Tetrahedron Letters, 27(6), 727-730. https://doi.org/10.1016/S0040-4039(00)84085-X