Total Synthesis And Absolute Configuration Of Sphingofungin D (N-Acetyl Asperfungin)

Noritaka Chida, Hiroyuki ikemoto, Aino Noguchi, Pilar Seiji Amano, Seiichiro Ogawa

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The total synthesis ot an antifungal novel amino acid derivative, sphingofungin D (N-acetyl asperfungin) starting from myoinositol and (fl)-epoxyoctane is described. This synthetic study showed that the undetermined stereochemistry at C-14 in sphingofungins should be R.

Original languageEnglish
Pages (from-to)295-302
Number of pages8
JournalNatural Product Letters
Volume6
Issue number4
DOIs
Publication statusPublished - 1995 Jun 1

Keywords

  • (R)-Epoxyoctane
  • Absolute Configuration
  • Asperfungin
  • Sphingofungins
  • myoinositol

ASJC Scopus subject areas

  • Molecular Medicine

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