Total synthesis of bafilomycin A1. 1. Syntheses of the C5-C11, C12-C17 and C18-C25 segments

Kazunobu Toshima, Takaaki Jyojima, Hiroyuki Yamaguchi, Hidekazu Murase, Taketo Yoshida, Shuichi Matsumura, Masaya Nakata

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

The effective syntheses of the C5-C11 (2), C12-C17 (3) and C18-C25 (4) segments, which are promising synthetic intermediates toward the total synthesis of the macrolide antibiotic, bafilomycin A1 (1), were described.

Original languageEnglish
Pages (from-to)1069-1072
Number of pages4
JournalTetrahedron Letters
Volume37
Issue number7
DOIs
Publication statusPublished - 1996 Feb 12

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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    Toshima, K., Jyojima, T., Yamaguchi, H., Murase, H., Yoshida, T., Matsumura, S., & Nakata, M. (1996). Total synthesis of bafilomycin A1. 1. Syntheses of the C5-C11, C12-C17 and C18-C25 segments. Tetrahedron Letters, 37(7), 1069-1072. https://doi.org/10.1016/0040-4039(95)02350-X