Total synthesis of bengamide E

Noritaka Chida; Takahiko Tobe; Seiichiro Ogawa

doi:10.1016/S0040-4039(00)74488-1

Total synthesis of bengamide E

Noritaka Chida, Takahiko Tobe, Seiichiro Ogawa

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

The first total synthesis of bengamide E (1), a novel sponge-derived amino acid, is described. The side chain of bengamide E (2) possessing four contiguous chiral centers was prepared in a stereoselective manner starting from naturally abundant cyclitol, l-quebrachitol.

Original language	English
Pages (from-to)	1063-1066
Number of pages	4
Journal	Tetrahedron Letters
Volume	32
Issue number	8
DOIs	https://doi.org/10.1016/S0040-4039(00)74488-1
Publication status	Published - 1991 Feb 18

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(00)74488-1

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title = "Total synthesis of bengamide E",

abstract = "The first total synthesis of bengamide E (1), a novel sponge-derived amino acid, is described. The side chain of bengamide E (2) possessing four contiguous chiral centers was prepared in a stereoselective manner starting from naturally abundant cyclitol, l-quebrachitol.",

author = "Noritaka Chida and Takahiko Tobe and Seiichiro Ogawa",

year = "1991",

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AU - Chida, Noritaka

AU - Tobe, Takahiko

AU - Ogawa, Seiichiro

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N2 - The first total synthesis of bengamide E (1), a novel sponge-derived amino acid, is described. The side chain of bengamide E (2) possessing four contiguous chiral centers was prepared in a stereoselective manner starting from naturally abundant cyclitol, l-quebrachitol.

AB - The first total synthesis of bengamide E (1), a novel sponge-derived amino acid, is described. The side chain of bengamide E (2) possessing four contiguous chiral centers was prepared in a stereoselective manner starting from naturally abundant cyclitol, l-quebrachitol.

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SP - 1063

EP - 1066

JO - Tetrahedron Letters

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Total synthesis of bengamide E

Abstract

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