Total synthesis of bengamide E

Noritaka Chida, Takahiko Tobe, Seiichiro Ogawa

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

The first total synthesis of bengamide E (1), a novel sponge-derived amino acid, is described. The side chain of bengamide E (2) possessing four contiguous chiral centers was prepared in a stereoselective manner starting from naturally abundant cyclitol, l-quebrachitol.

Original languageEnglish
Pages (from-to)1063-1066
Number of pages4
JournalTetrahedron Letters
Volume32
Issue number8
DOIs
Publication statusPublished - 1991 Feb 18

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Cyclitols
Porifera
Amino Acids
bengamide E
quebrachitol

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Total synthesis of bengamide E. / Chida, Noritaka; Tobe, Takahiko; Ogawa, Seiichiro.

In: Tetrahedron Letters, Vol. 32, No. 8, 18.02.1991, p. 1063-1066.

Research output: Contribution to journalArticle

Chida, Noritaka ; Tobe, Takahiko ; Ogawa, Seiichiro. / Total synthesis of bengamide E. In: Tetrahedron Letters. 1991 ; Vol. 32, No. 8. pp. 1063-1066.
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