Total synthesis of biselyngbyolide A

Yurika Tanabe, Eisuke Sato, Naoya Nakajima, Akifumi Ohkubo, Osamu Ohno, Kiyotake Suenaga

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Biselyngbyolide A is an 18-membered macrolide that exhibits significant biological activities such as growth-inhibitory activity and apoptosis inducing activity against cancer cells. In this study, the first total synthesis of biselyngbyolide A by using an intramolecular Stille coupling reaction as a key step is achieved.

Original languageEnglish
Pages (from-to)2858-2861
Number of pages4
JournalOrganic Letters
Volume16
Issue number11
DOIs
Publication statusPublished - 2014 Jun 6

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Macrolides
apoptosis
synthesis
activity (biology)
Bioactivity
cancer
Cells
Apoptosis
Growth
Neoplasms
biselyngbyolide A

ASJC Scopus subject areas

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

Cite this

Tanabe, Y., Sato, E., Nakajima, N., Ohkubo, A., Ohno, O., & Suenaga, K. (2014). Total synthesis of biselyngbyolide A. Organic Letters, 16(11), 2858-2861. https://doi.org/10.1021/ol500996n

Total synthesis of biselyngbyolide A. / Tanabe, Yurika; Sato, Eisuke; Nakajima, Naoya; Ohkubo, Akifumi; Ohno, Osamu; Suenaga, Kiyotake.

In: Organic Letters, Vol. 16, No. 11, 06.06.2014, p. 2858-2861.

Research output: Contribution to journalArticle

Tanabe, Y, Sato, E, Nakajima, N, Ohkubo, A, Ohno, O & Suenaga, K 2014, 'Total synthesis of biselyngbyolide A', Organic Letters, vol. 16, no. 11, pp. 2858-2861. https://doi.org/10.1021/ol500996n
Tanabe Y, Sato E, Nakajima N, Ohkubo A, Ohno O, Suenaga K. Total synthesis of biselyngbyolide A. Organic Letters. 2014 Jun 6;16(11):2858-2861. https://doi.org/10.1021/ol500996n
Tanabe, Yurika ; Sato, Eisuke ; Nakajima, Naoya ; Ohkubo, Akifumi ; Ohno, Osamu ; Suenaga, Kiyotake. / Total synthesis of biselyngbyolide A. In: Organic Letters. 2014 ; Vol. 16, No. 11. pp. 2858-2861.
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