Total synthesis of (-)-brevisin: A concise synthesis of a new marine polycyclic ether

Takefumi Kuranaga, Naohito Ohtani, Ryosuke Tsutsumi, Daniel G. Baden, Jeffrey L.C. Wright, Masayuki Satake, Kazuo Tachibana

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

The first and highly efficient total synthesis of (-)-brevisin has been achieved. The title compound was synthesized in only 29 steps (longest linear sequence) from commercially available starting materials. The synthesis provided over 70 mg of a marine polycyclic ether compound.

Original languageEnglish
Pages (from-to)696-699
Number of pages4
JournalOrganic Letters
Volume13
Issue number4
DOIs
Publication statusPublished - 2011 Feb 18
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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