Total synthesis of (+)-cheimonophyllon E, a bisabolane sesquiterpenoid

Kenichi Takao, Manabu Hara, Tomohiro Tsujita, Ken Ichi Yoshida, Kin Ichi Tadano

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Total synthesis of (±)-cheimonophyllon E was accomplished starting from 3-methyl-2-cyclohexen-1-one. Also, synthesis of (+)-cheimonophyllon E, the natural enantiomer, was achieved through optical resolution of a key intermediate in the racemic synthesis.

Original languageEnglish
Pages (from-to)4665-4668
Number of pages4
JournalTetrahedron Letters
Volume42
Issue number28
DOIs
Publication statusPublished - 2001 Jul 9

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Enantiomers
3-methyl-2-cyclohexen-1-one

Keywords

  • Biologically active compounds
  • Cyclization
  • Resolution
  • Terpenes and terpenoids

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Total synthesis of (+)-cheimonophyllon E, a bisabolane sesquiterpenoid. / Takao, Kenichi; Hara, Manabu; Tsujita, Tomohiro; Yoshida, Ken Ichi; Tadano, Kin Ichi.

In: Tetrahedron Letters, Vol. 42, No. 28, 09.07.2001, p. 4665-4668.

Research output: Contribution to journalArticle

Takao, Kenichi ; Hara, Manabu ; Tsujita, Tomohiro ; Yoshida, Ken Ichi ; Tadano, Kin Ichi. / Total synthesis of (+)-cheimonophyllon E, a bisabolane sesquiterpenoid. In: Tetrahedron Letters. 2001 ; Vol. 42, No. 28. pp. 4665-4668.
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