Total synthesis of indole alkaloids using oxidative coupling reaction

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Abstract

A novel direct oxidative coupling reaction between carbonyl groups and indoles was recently developed. Total syntheses of highly functionalized natural products, (+)-hapalindole and (+)-welwitindolinone, were achieved using the new method. The present coupling strategy makes the synthesis of indole alkaloids highly concise and practical.

Original languageEnglish
Pages (from-to)679-680
Number of pages2
JournalYuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
Volume64
Issue number6
Publication statusPublished - 2006 Jun
Externally publishedYes

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Indole Alkaloids
Indoles
Biological Products

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

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abstract = "A novel direct oxidative coupling reaction between carbonyl groups and indoles was recently developed. Total syntheses of highly functionalized natural products, (+)-hapalindole and (+)-welwitindolinone, were achieved using the new method. The present coupling strategy makes the synthesis of indole alkaloids highly concise and practical.",
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