A novel direct oxidative coupling reaction between carbonyl groups and indoles was recently developed. Total syntheses of highly functionalized natural products, (+)-hapalindole and (+)-welwitindolinone, were achieved using the new method. The present coupling strategy makes the synthesis of indole alkaloids highly concise and practical.
|Number of pages||2|
|Journal||Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry|
|Publication status||Published - 2006 Jun|
ASJC Scopus subject areas
- Organic Chemistry