Total synthesis of naturally occurring chiral cyclopropane fatty acids and related compounds

Shinsuke Inuki, Yukari Fujimoto

Research output: Contribution to journalReview article

Abstract

Cyclopropane fatty acids (CFAs) and related compounds containing CFAs commonly occur in various natural sources, including plants or microorganisms. Some CFAs exhibit intriguing biological activities such as antifungal or immunosuppressive activities. Due to their biological importance and structural features, a number of synthetic studies have been conducted to date. These total syntheses have helped to elucidate their structural determinants or biological activities. Herein the total syntheses of naturally occurring CFAs and related compounds are summarized.

Original languageEnglish
Pages (from-to)1083-1090
Number of pages8
JournalTetrahedron Letters
Volume60
Issue number16
DOIs
Publication statusPublished - 2019 Apr 18

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Bioactivity
Immunosuppressive Agents
Microorganisms
cyclopropane fatty acids

Keywords

  • Biological activity
  • Cyclopropane fatty acid
  • Structural determination
  • Total synthesis

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Total synthesis of naturally occurring chiral cyclopropane fatty acids and related compounds. / Inuki, Shinsuke; Fujimoto, Yukari.

In: Tetrahedron Letters, Vol. 60, No. 16, 18.04.2019, p. 1083-1090.

Research output: Contribution to journalReview article

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