Total Synthesis of Paecilomycin B

Kiyomi Ohba, Masaya Nakata

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Starting from the glucose-derived δ-lactone and the functionalized aryl bromide, the first total synthesis of naturally occurring paecilomycin B was achieved via functionalized aryl-β-C-glycoside synthesis using 2,4,6-triisopropylphenyllithium under Barbier-type reaction conditions and ring-closing metathesis as the key steps.

Original languageEnglish
Pages (from-to)2890-2893
Number of pages4
JournalOrganic Letters
Volume17
Issue number12
DOIs
Publication statusPublished - 2015 Jun 19

ASJC Scopus subject areas

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

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