Total synthesis of phenoxan and a related pyrone derivative

Yasuharu Ishibashi; Shigeru Ohba; Shigeru Nishiyama; Shosuke Yamamura

doi:10.1016/0040-4039(96)00483-2

Total synthesis of phenoxan and a related pyrone derivative

Yasuharu Ishibashi, Shigeru Ohba, Shigeru Nishiyama, Shosuke Yamamura

Department of Humanities and Social Sciences

Research output: Contribution to journal › Article › peer-review

45 Citations (Scopus)

Abstract

Phenoxan, HIV-1 inhibitor isolated from the myxobacteria, has been synthesized in 16 steps starting from ethyl 2-methylacetoacetate. The related isomer corresponding to the oxazole part was also obtained via an orthoester-enediol rearrangement.

Original language	English
Pages (from-to)	2997-3000
Number of pages	4
Journal	Tetrahedron Letters
Volume	37
Issue number	17
DOIs	https://doi.org/10.1016/0040-4039(96)00483-2
Publication status	Published - 1996 Apr 22

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/0040-4039(96)00483-2

Cite this

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title = "Total synthesis of phenoxan and a related pyrone derivative",

abstract = "Phenoxan, HIV-1 inhibitor isolated from the myxobacteria, has been synthesized in 16 steps starting from ethyl 2-methylacetoacetate. The related isomer corresponding to the oxazole part was also obtained via an orthoester-enediol rearrangement.",

author = "Yasuharu Ishibashi and Shigeru Ohba and Shigeru Nishiyama and Shosuke Yamamura",

year = "1996",

month = apr,

day = "22",

doi = "10.1016/0040-4039(96)00483-2",

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journal = "Tetrahedron Letters",

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T1 - Total synthesis of phenoxan and a related pyrone derivative

AU - Ishibashi, Yasuharu

AU - Ohba, Shigeru

AU - Nishiyama, Shigeru

AU - Yamamura, Shosuke

PY - 1996/4/22

Y1 - 1996/4/22

N2 - Phenoxan, HIV-1 inhibitor isolated from the myxobacteria, has been synthesized in 16 steps starting from ethyl 2-methylacetoacetate. The related isomer corresponding to the oxazole part was also obtained via an orthoester-enediol rearrangement.

AB - Phenoxan, HIV-1 inhibitor isolated from the myxobacteria, has been synthesized in 16 steps starting from ethyl 2-methylacetoacetate. The related isomer corresponding to the oxazole part was also obtained via an orthoester-enediol rearrangement.

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U2 - 10.1016/0040-4039(96)00483-2

DO - 10.1016/0040-4039(96)00483-2

M3 - Article

AN - SCOPUS:0029876114

SN - 0040-4039

VL - 37

SP - 2997

EP - 3000

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 17

ER -

Total synthesis of phenoxan and a related pyrone derivative

Abstract

ASJC Scopus subject areas

UN SDGs

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