Total synthesis of (-)-Pramanicin

Shin ya Aoki; Taro Tsukude; Yukari Miyazaki; Ken ichi Takao; Kin ichi Tadano

doi:10.3987/com-06-s(o)5

Total synthesis of (-)-Pramanicin

Shin ya Aoki, Taro Tsukude, Yukari Miyazaki, Ken ichi Takao, Kin ichi Tadano

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

The total synthesis of natural (-)-pramanicin, a highly oxygenated γlactam-type antifungal agent, is described. The enantiospecific total synthesis of this natural product commenced with 5-deoxy-1,2-O-isopropylidene-α-d-xylofuranose as an enantiopure starting material.

Original language	English
Pages (from-to)	49-54
Number of pages	6
Journal	Heterocycles
Volume	69
Issue number	1
DOIs	https://doi.org/10.3987/com-06-s(o)5
Publication status	Published - 2006 Dec 1

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

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title = "Total synthesis of (-)-Pramanicin",

abstract = "The total synthesis of natural (-)-pramanicin, a highly oxygenated γlactam-type antifungal agent, is described. The enantiospecific total synthesis of this natural product commenced with 5-deoxy-1,2-O-isopropylidene-α-d-xylofuranose as an enantiopure starting material.",

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AU - Aoki, Shin ya

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AU - Miyazaki, Yukari

AU - Takao, Ken ichi

AU - Tadano, Kin ichi

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Y1 - 2006/12/1

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AB - The total synthesis of natural (-)-pramanicin, a highly oxygenated γlactam-type antifungal agent, is described. The enantiospecific total synthesis of this natural product commenced with 5-deoxy-1,2-O-isopropylidene-α-d-xylofuranose as an enantiopure starting material.

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Total synthesis of (-)-Pramanicin

Abstract

ASJC Scopus subject areas

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