Total synthesis of rifamycin W

Masaya Nakata, Nobutake Akiyama, Kyoko Kojima, Hirokazu Masuda, Mitsuhiro Kinoshita, Kuniaki Tatsuta

Research output: Contribution to journalArticle

12 Citations (Scopus)


The first total synthesis of rifamycin W (1) has been accomplished by coupling two segments of the aliphatic ansa-chain 2 and the aromatic chromophore 3, elucidating the absolute structure completely.

Original languageEnglish
Pages (from-to)1585-1588
Number of pages4
JournalTetrahedron Letters
Issue number11
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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    Nakata, M., Akiyama, N., Kojima, K., Masuda, H., Kinoshita, M., & Tatsuta, K. (1990). Total synthesis of rifamycin W. Tetrahedron Letters, 31(11), 1585-1588.