@article{1226108a83c94eef9cc67ccfe3adafd5,
title = "Toward bioluminescence in the near-infrared region: Tuning the emission wavelength of firefly luciferin analogues by allyl substitution",
abstract = "The synthesis and bioluminescence of allyl-substituted luciferin derivatives as substrates for firefly luciferase are reported. The allylation of luciferins induced bathochromic shift (15–40 nm) of the bioluminescence emission. Upon combination with other chemical modifications for bioluminescence wavelength tuning, novel red emitting luciferin analogues were obtained with emission maxima at 685 and 690 nm.",
keywords = "Bioluminescence, Firefly, Luciferin derivatives, Near infrared",
author = "Nobuo Kitada and Tsuyoshi Saitoh and Yuma Ikeda and Satoshi Iwano and Rika Obata and Haruki Niwa and Takashi Hirano and Atsushi Miyawaki and Koji Suzuki and Shigeru Nishiyama and Maki, {Shojiro A.}",
note = "Funding Information: This work was supported by the Grant-in-Aid for Scientific Research on Innovative Areas “Resonance Bio” (15H05948; S.A.M.) and a JSPS research fellowship for young scientists (N.K.) from the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Adaptable & Seamless Technology Transfer Program through Target-driven R&D (A-Step) (AS2614119N; S.A.M.) from the Japan Science and Technology Agency (JST), and a Kurata grant (1207; T.S.) from the Kurata Memorial Hitachi Science and Technology Foundation . ",
year = "2018",
month = mar,
day = "21",
doi = "10.1016/j.tetlet.2018.01.078",
language = "English",
volume = "59",
pages = "1087--1090",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "12",
}