Toxic principles of a poisonous mushroom Podostroma cornu-damae

Yoko Saikawa, Hiroki Okamoto, Taichi Inui, Midori Makabe, Toshikatsu Okuno, Takashi Suda, Kimiko Hashimoto, Masaya Nakata

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

From the culture broth of a poisonous mushroom Podostroma cornu-damae, roridin E, verrucarin J, and satratoxin H were isolated. From the fruit bodies of the same fungus, satratoxin H, satratoxin H 12′,13′-diacetate, satratoxin H 12′-acetate, and satratoxin H 13′-acetate were isolated. All these macrocyclic trichothecenes except for verrucarin J had a lethal effect on mice by at least 0.5 mg per capita.

Original languageEnglish
Pages (from-to)8277-8281
Number of pages5
JournalTetrahedron
Volume57
Issue number39
DOIs
Publication statusPublished - 2001 Sep 24

Keywords

  • Hypocreaceae
  • Lethal toxins
  • Mushroom
  • Podostroma cornu-damae
  • Roridin E
  • Satratoxin H
  • Satratoxin H 12′,13′-diacetate
  • Satratoxin H 12′-acetate
  • Satratoxin H 13′-acetate
  • Trichothecenes
  • Verrucarin J

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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  • Cite this

    Saikawa, Y., Okamoto, H., Inui, T., Makabe, M., Okuno, T., Suda, T., Hashimoto, K., & Nakata, M. (2001). Toxic principles of a poisonous mushroom Podostroma cornu-damae. Tetrahedron, 57(39), 8277-8281. https://doi.org/10.1016/S0040-4020(01)00824-9