Abstract
From the culture broth of a poisonous mushroom Podostroma cornu-damae, roridin E, verrucarin J, and satratoxin H were isolated. From the fruit bodies of the same fungus, satratoxin H, satratoxin H 12′,13′-diacetate, satratoxin H 12′-acetate, and satratoxin H 13′-acetate were isolated. All these macrocyclic trichothecenes except for verrucarin J had a lethal effect on mice by at least 0.5 mg per capita.
Original language | English |
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Pages (from-to) | 8277-8281 |
Number of pages | 5 |
Journal | Tetrahedron |
Volume | 57 |
Issue number | 39 |
DOIs | |
Publication status | Published - 2001 Sept 24 |
Keywords
- Hypocreaceae
- Lethal toxins
- Mushroom
- Podostroma cornu-damae
- Roridin E
- Satratoxin H
- Satratoxin H 12′,13′-diacetate
- Satratoxin H 12′-acetate
- Satratoxin H 13′-acetate
- Trichothecenes
- Verrucarin J
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry