Trabeculectomy with the use of amniotic membrane for uncontrollable glaucoma

Hiroshi Fujishima, Jun Shimazaki, Naoshi Shinozaki, Kazuo Tsubota

Research output: Contribution to journalArticle

82 Citations (Scopus)

Abstract

Although trabeculectomy is an established surgical technique for glaucoma, in some cases it does not achieve a good filtering effect despite the use of mitomycin-C (MMC). The authors have developed a new surgical technique for uncontrollable glaucoma that uses amniotic membrane to prevent postoperative adhesion of conjunctiva and sclera. They performed trabeculectomy with a limbal-based conjunctival flap using 0.4 mg/ml of MMC for 2 minutes. Amniotic membrane was then placed under the scleral flap and sutured using 10-0 nylon. Among 14 eyes of 13 patients who underwent this procedure, intraocular pressure was controlled to less than 20 mm Hg after surgery in 13 eyes, including 3 eyes that underwent a second surgery with the same technique and 2 eyes that underwent laser trabeculoplasty. The authors' results suggest that this technique is efficacious for the reduction of intraocular pressure in high-risk glaucoma patients.

Original languageEnglish
Pages (from-to)428-431
Number of pages4
JournalOphthalmic Surgery and Lasers
Volume29
Issue number5
Publication statusPublished - 1998 May

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Trabeculectomy
Amnion
Glaucoma
Mitomycin
Intraocular Pressure
Sclera
Conjunctiva
Nylons
Lasers

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Trabeculectomy with the use of amniotic membrane for uncontrollable glaucoma. / Fujishima, Hiroshi; Shimazaki, Jun; Shinozaki, Naoshi; Tsubota, Kazuo.

In: Ophthalmic Surgery and Lasers, Vol. 29, No. 5, 05.1998, p. 428-431.

Research output: Contribution to journalArticle

Fujishima, H, Shimazaki, J, Shinozaki, N & Tsubota, K 1998, 'Trabeculectomy with the use of amniotic membrane for uncontrollable glaucoma', Ophthalmic Surgery and Lasers, vol. 29, no. 5, pp. 428-431.
Fujishima, Hiroshi ; Shimazaki, Jun ; Shinozaki, Naoshi ; Tsubota, Kazuo. / Trabeculectomy with the use of amniotic membrane for uncontrollable glaucoma. In: Ophthalmic Surgery and Lasers. 1998 ; Vol. 29, No. 5. pp. 428-431.
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