Traction force of smooth muscle cell during growth on a rigid substrate

U. G. Jung, T. Tsukagoshi, Hidetoshi Takahashi, T. Kan, K. Matsumoto, I. Shimoyama

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Citations (Scopus)

Abstract

This paper reports on the sensor for traction force measurement of a smooth muscle cell during cell growth on a rigid substrate, specially designed for horizontal and vertical directional forces. For quantitative measurement, the cells are cultured only on the sensor pads using a cover chip. The length of the sensor is 1130μm. The size of the sensor pad is 125μm×15μ m×5μm (length×width× thickness). The gaps between the sensor pads are 3μm. We confirmed that the cells spread on the two sensor pads at least. We measured the traction forces of bovine aortic smooth muscle cells (BAOSMCs, CAB35405) using the proposed sensor. When the three cells spread on the pads, the measured traction forces in x and z direction increased 30nN and 20nN for 8 min, respectively.

Original languageEnglish
Title of host publicationMEMS 2014 - 27th IEEE International Conference on Micro Electro Mechanical Systems
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages290-293
Number of pages4
ISBN (Print)9781479935086
DOIs
Publication statusPublished - 2014 Jan 1
Externally publishedYes
Event27th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2014 - San Francisco, CA, United States
Duration: 2014 Jan 262014 Jan 30

Publication series

NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)1084-6999

Other

Other27th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2014
CountryUnited States
CitySan Francisco, CA
Period14/1/2614/1/30

Fingerprint

smooth muscle
muscle cells
traction
Cell growth
Muscle
sensors
Sensors
Substrates
Cells
Force measurement
cells
cultured cells
chips

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

Cite this

Jung, U. G., Tsukagoshi, T., Takahashi, H., Kan, T., Matsumoto, K., & Shimoyama, I. (2014). Traction force of smooth muscle cell during growth on a rigid substrate. In MEMS 2014 - 27th IEEE International Conference on Micro Electro Mechanical Systems (pp. 290-293). [6765634] (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MEMSYS.2014.6765633

Traction force of smooth muscle cell during growth on a rigid substrate. / Jung, U. G.; Tsukagoshi, T.; Takahashi, Hidetoshi; Kan, T.; Matsumoto, K.; Shimoyama, I.

MEMS 2014 - 27th IEEE International Conference on Micro Electro Mechanical Systems. Institute of Electrical and Electronics Engineers Inc., 2014. p. 290-293 6765634 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Jung, UG, Tsukagoshi, T, Takahashi, H, Kan, T, Matsumoto, K & Shimoyama, I 2014, Traction force of smooth muscle cell during growth on a rigid substrate. in MEMS 2014 - 27th IEEE International Conference on Micro Electro Mechanical Systems., 6765634, Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), Institute of Electrical and Electronics Engineers Inc., pp. 290-293, 27th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2014, San Francisco, CA, United States, 14/1/26. https://doi.org/10.1109/MEMSYS.2014.6765633
Jung UG, Tsukagoshi T, Takahashi H, Kan T, Matsumoto K, Shimoyama I. Traction force of smooth muscle cell during growth on a rigid substrate. In MEMS 2014 - 27th IEEE International Conference on Micro Electro Mechanical Systems. Institute of Electrical and Electronics Engineers Inc. 2014. p. 290-293. 6765634. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2014.6765633
Jung, U. G. ; Tsukagoshi, T. ; Takahashi, Hidetoshi ; Kan, T. ; Matsumoto, K. ; Shimoyama, I. / Traction force of smooth muscle cell during growth on a rigid substrate. MEMS 2014 - 27th IEEE International Conference on Micro Electro Mechanical Systems. Institute of Electrical and Electronics Engineers Inc., 2014. pp. 290-293 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).
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