TY - JOUR
T1 - Transcorneal electrical stimulation of retina to treat longstanding retinal artery occlusion
AU - Inomata, Koichi
AU - Shinoda, Kei
AU - Ohde, Hisao
AU - Tsunoda, Kazushige
AU - Hanazono, Gen
AU - Kimura, Itaru
AU - Yuzawa, Mitsuko
AU - Tsubota, Kazuo
AU - Miyake, Yozo
N1 - Funding Information:
None of the authors have any financial or proprietary interest in any material or methods mentioned. This study was supported by Researches on Sensory and Communicative Disorders from the Ministry of Health, Labor, and Welfare, Japan. K.Inomata.K.Shinoda(*).H.Ohde.K.Tsunoda. G. Hanazono.Y. Miyake Laboratory of Visual Physiology, National Institute of Sensory Organs, National Hospital Organization, Tokyo Medical Center, 2-5-1 Higashigaoka, Meguro-ku, Tokyo 152-8902, Japan e-mail: shinodakei@kankakuki.go.jp
PY - 2007/12
Y1 - 2007/12
N2 - Purpose: To report the outcome of transcorneal electrical stimulation (TES) of the visual system on long-standing retinal artery occlusion (RAO). Design: Open labeled, case series. Patients and methods: Two patients with central RAO (15 and 33 months respectively) and one with branch RAO (26 months) underwent TES therapy. Subjective and objective ophthalmological evaluations were performed before and after the TES. The ages of the patients were 38, 49, and 63 years. The TES (20 Hz biphasic pulses, 30 minutes, up to 1100 uA) was delivered by a bipolar contact lens electrode once a month for 3 months. Perimetric and/or electrophysiological examinations were performed as outcome measures. Results: The visual acuity improved by more than 0.2 logMAR units in two cases, and the visual fields were improved in all three cases. The multifocal ERGs which had been reduced in the loci corresponding to the ischemic retinal area were improved after the treatment in two cases. Neither ocular nor systemic adverse effects were observed except for transient superficial keratitis. Conclusions: TES of the retina can improve retinal function in eyes with long-standing RAOs.
AB - Purpose: To report the outcome of transcorneal electrical stimulation (TES) of the visual system on long-standing retinal artery occlusion (RAO). Design: Open labeled, case series. Patients and methods: Two patients with central RAO (15 and 33 months respectively) and one with branch RAO (26 months) underwent TES therapy. Subjective and objective ophthalmological evaluations were performed before and after the TES. The ages of the patients were 38, 49, and 63 years. The TES (20 Hz biphasic pulses, 30 minutes, up to 1100 uA) was delivered by a bipolar contact lens electrode once a month for 3 months. Perimetric and/or electrophysiological examinations were performed as outcome measures. Results: The visual acuity improved by more than 0.2 logMAR units in two cases, and the visual fields were improved in all three cases. The multifocal ERGs which had been reduced in the loci corresponding to the ischemic retinal area were improved after the treatment in two cases. Neither ocular nor systemic adverse effects were observed except for transient superficial keratitis. Conclusions: TES of the retina can improve retinal function in eyes with long-standing RAOs.
KW - Branch retinal artery occlusion
KW - Central retinal artery occlusion
KW - Electrical stimulation
KW - Phosphene
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U2 - 10.1007/s00417-007-0610-9
DO - 10.1007/s00417-007-0610-9
M3 - Article
C2 - 17593383
AN - SCOPUS:36348991883
SN - 0065-6100
VL - 245
SP - 1773
EP - 1780
JO - Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie
JF - Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie
IS - 12
ER -