Transcriptome analysis reveals two distinct endotypes and putative immune pathways in tonsils from children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome

Mariko Hara; Noriko Morimoto; Noriomi Suzuki; Nana Tsuchihashi; Manabu Komori; Keisuke Yoshihama; Kae Fujii; Sota Yamaguchi; Mayumi Tsunoda; Syuta Tomisato; Nozomi Takahashi; Koichiro Oyake; Yuzuru Okuba; Mikiya Fujieda; Kenji Matsumoto

doi:10.1111/all.14477

Transcriptome analysis reveals two distinct endotypes and putative immune pathways in tonsils from children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome

Mariko Hara, Noriko Morimoto, Noriomi Suzuki, Nana Tsuchihashi, Manabu Komori, Keisuke Yoshihama, Kae Fujii, Sota Yamaguchi, Mayumi Tsunoda, Syuta Tomisato, Nozomi Takahashi, Koichiro Oyake, Yuzuru Okuba, Mikiya Fujieda, Kenji Matsumoto

Research output: Contribution to journal › Letter › peer-review

4 Citations (Scopus)

Original language	English
Pages (from-to)	359-363
Number of pages	5
Journal	Allergy: European Journal of Allergy and Clinical Immunology
Volume	76
Issue number	1
DOIs	https://doi.org/10.1111/all.14477
Publication status	Published - 2021 Jan
Externally published	Yes

Keywords

PFAPA syndrome
endotype
innate immune response
phenotype
tonsil

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1111/all.14477

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Hara, M., Morimoto, N., Suzuki, N., Tsuchihashi, N., Komori, M., Yoshihama, K., Fujii, K., Yamaguchi, S., Tsunoda, M., Tomisato, S., Takahashi, N., Oyake, K., Okuba, Y., Fujieda, M., & Matsumoto, K. (2021). Transcriptome analysis reveals two distinct endotypes and putative immune pathways in tonsils from children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome. Allergy: European Journal of Allergy and Clinical Immunology, 76(1), 359-363. https://doi.org/10.1111/all.14477

Transcriptome analysis reveals two distinct endotypes and putative immune pathways in tonsils from children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome. / Hara, Mariko; Morimoto, Noriko; Suzuki, Noriomi et al.

In: Allergy: European Journal of Allergy and Clinical Immunology, Vol. 76, No. 1, 01.2021, p. 359-363.

Research output: Contribution to journal › Letter › peer-review

Hara, M, Morimoto, N, Suzuki, N, Tsuchihashi, N, Komori, M, Yoshihama, K, Fujii, K, Yamaguchi, S, Tsunoda, M, Tomisato, S, Takahashi, N, Oyake, K, Okuba, Y, Fujieda, M & Matsumoto, K 2021, 'Transcriptome analysis reveals two distinct endotypes and putative immune pathways in tonsils from children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome', Allergy: European Journal of Allergy and Clinical Immunology, vol. 76, no. 1, pp. 359-363. https://doi.org/10.1111/all.14477

Hara M, Morimoto N, Suzuki N, Tsuchihashi N, Komori M, Yoshihama K et al. Transcriptome analysis reveals two distinct endotypes and putative immune pathways in tonsils from children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome. Allergy: European Journal of Allergy and Clinical Immunology. 2021 Jan;76(1):359-363. doi: 10.1111/all.14477

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title = "Transcriptome analysis reveals two distinct endotypes and putative immune pathways in tonsils from children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome",

keywords = "PFAPA syndrome, endotype, innate immune response, phenotype, tonsil",

author = "Mariko Hara and Noriko Morimoto and Noriomi Suzuki and Nana Tsuchihashi and Manabu Komori and Keisuke Yoshihama and Kae Fujii and Sota Yamaguchi and Mayumi Tsunoda and Syuta Tomisato and Nozomi Takahashi and Koichiro Oyake and Yuzuru Okuba and Mikiya Fujieda and Kenji Matsumoto",

note = "Funding Information: The authors thank Ms Yoshiko Shimamoto and Ms Kazue Takeda of the Department of Allergy and Clinical Immunology, National Research Institute for Child Health and Development for their excellent technical assistance. This study was supported in part by grants from Kawano Masanori Memorial Public Interest Incorporated Foundation for Promotion of Pediatrics (to M. H.), from The Ministry of Education, Culture, Sports, Science, and Technology (MEXT: 18K15695 and 20K16910) to M. H., and from The Japan Agency for Medical Research and Development (AMED: 17ek0109278h0001) to K. M. Funding Information: The authors thank Ms Yoshiko Shimamoto and Ms Kazue Takeda of the Department of Allergy and Clinical Immunology, National Research Institute for Child Health and Development for their excellent technical assistance. This study was supported in part by grants from Kawano Masanori Memorial Public Interest Incorporated Foundation for Promotion of Pediatrics (to M. H.), from The Ministry of Education, Culture, Sports, Science, and Technology (MEXT: 18K15695 and 20K16910) to M. H., and from The Japan Agency for Medical Research and Development (AMED: 17ek0109278h0001) to K. M.",

year = "2021",

month = jan,

doi = "10.1111/all.14477",

language = "English",

volume = "76",

pages = "359--363",

journal = "Allergy: European Journal of Allergy and Clinical Immunology",

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T1 - Transcriptome analysis reveals two distinct endotypes and putative immune pathways in tonsils from children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome

AU - Hara, Mariko

AU - Morimoto, Noriko

AU - Suzuki, Noriomi

AU - Tsuchihashi, Nana

AU - Komori, Manabu

AU - Yoshihama, Keisuke

AU - Fujii, Kae

AU - Yamaguchi, Sota

AU - Tsunoda, Mayumi

AU - Tomisato, Syuta

AU - Takahashi, Nozomi

AU - Oyake, Koichiro

AU - Okuba, Yuzuru

AU - Fujieda, Mikiya

AU - Matsumoto, Kenji

N1 - Funding Information: The authors thank Ms Yoshiko Shimamoto and Ms Kazue Takeda of the Department of Allergy and Clinical Immunology, National Research Institute for Child Health and Development for their excellent technical assistance. This study was supported in part by grants from Kawano Masanori Memorial Public Interest Incorporated Foundation for Promotion of Pediatrics (to M. H.), from The Ministry of Education, Culture, Sports, Science, and Technology (MEXT: 18K15695 and 20K16910) to M. H., and from The Japan Agency for Medical Research and Development (AMED: 17ek0109278h0001) to K. M. Funding Information: The authors thank Ms Yoshiko Shimamoto and Ms Kazue Takeda of the Department of Allergy and Clinical Immunology, National Research Institute for Child Health and Development for their excellent technical assistance. This study was supported in part by grants from Kawano Masanori Memorial Public Interest Incorporated Foundation for Promotion of Pediatrics (to M. H.), from The Ministry of Education, Culture, Sports, Science, and Technology (MEXT: 18K15695 and 20K16910) to M. H., and from The Japan Agency for Medical Research and Development (AMED: 17ek0109278h0001) to K. M.

PY - 2021/1

Y1 - 2021/1

KW - PFAPA syndrome

KW - endotype

KW - innate immune response

KW - phenotype

KW - tonsil

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Transcriptome analysis reveals two distinct endotypes and putative immune pathways in tonsils from children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome

Keywords

ASJC Scopus subject areas

Access to Document

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