Transcutaneous biochemical substance monitoring based on biosensors - blood glucose and lactate

Makoto Kikuchi, Shinsuke Kayashima, Narushi Ito, Tsunenori Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

New transcutaneous monitoring methods for biochemical substances such as blood glucose and lactate have been developed by using a suction effusion fluid (SEF) collecting technique with an ion-sensitive field-effect transistor for blood glucose, and with a micro-planar amperometric biosensor for lactate respectively. Firstly, blood glucose change during the 75-g oral glucose tolerance test (OGTT) was monitored by suction effusion fluid (SEF) sampling in five patients with type II diabetes. Secondly, we have also developed a micro-planar biosensor for determining lactate concentration in very small sample. The biosensor utilizes a lactate oxidase immobilizes membrane on a micro planar platinum electrode to yield a lactate sensor. Both glucose and lactate concentrations measured with SEF showed good correlation with those obtained directly from whole blood.

Original languageEnglish
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
PublisherIEEE
Pages91-92
Number of pages2
Edition1
Publication statusPublished - 1996
Externally publishedYes
EventProceedings of the 1996 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 2 (of 5) - Amsterdam, Neth
Duration: 1996 Oct 311996 Nov 3

Other

OtherProceedings of the 1996 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 2 (of 5)
CityAmsterdam, Neth
Period96/10/3196/11/3

Fingerprint

Biosensors
Glucose
Blood Glucose
Lactic Acid
Blood
Monitoring
lactate 2-monooxygenase
Fluids
Ion sensitive field effect transistors
Medical problems
Platinum
Sampling
Membranes
Electrodes
Sensors

ASJC Scopus subject areas

  • Bioengineering

Cite this

Kikuchi, M., Kayashima, S., Ito, N., & Arai, T. (1996). Transcutaneous biochemical substance monitoring based on biosensors - blood glucose and lactate. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (1 ed., pp. 91-92). IEEE.

Transcutaneous biochemical substance monitoring based on biosensors - blood glucose and lactate. / Kikuchi, Makoto; Kayashima, Shinsuke; Ito, Narushi; Arai, Tsunenori.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 1. ed. IEEE, 1996. p. 91-92.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kikuchi, M, Kayashima, S, Ito, N & Arai, T 1996, Transcutaneous biochemical substance monitoring based on biosensors - blood glucose and lactate. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 1 edn, IEEE, pp. 91-92, Proceedings of the 1996 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 2 (of 5), Amsterdam, Neth, 96/10/31.
Kikuchi M, Kayashima S, Ito N, Arai T. Transcutaneous biochemical substance monitoring based on biosensors - blood glucose and lactate. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 1 ed. IEEE. 1996. p. 91-92
Kikuchi, Makoto ; Kayashima, Shinsuke ; Ito, Narushi ; Arai, Tsunenori. / Transcutaneous biochemical substance monitoring based on biosensors - blood glucose and lactate. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 1. ed. IEEE, 1996. pp. 91-92
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