Transcutaneous biochemical substance monitoring based on biosensors - blood glucose and lactate

Makoto Kikuchi, Shinsuke Kayashima, Narushi Ito, Tsunenori Arai

Research output: Contribution to journalConference article

Abstract

New transcutaneous monitoring methods for biochemical substances such as blood glucose and lactate have been developed by using a suction effusion fluid (SEF) collecting technique with an ion-sensitive field-effect transistor for blood glucose, and with a micro-planar amperometric biosensor for lactate respectively. Firstly, blood glucose change during the 75-g oral glucose tolerance test (OGTT) was monitored by suction effusion fluid (SEF) sampling in five patients with type II diabetes. Secondly, we have also developed a micro-planar biosensor for determining lactate concentration in very small sample. The biosensor utilizes a lactate oxidase immobilizes membrane on a micro planar platinum electrode to yield a lactate sensor. Both glucose and lactate concentrations measured with SEF showed good correlation with those obtained directly from whole blood.

Original languageEnglish
Pages (from-to)91-92
Number of pages2
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Issue number1
Publication statusPublished - 1996 Dec 1
EventProceedings of the 1996 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 2 (of 5) - Amsterdam, Neth
Duration: 1996 Oct 311996 Nov 3

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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