Transient increase in systemic interferences in the superficial layer and its influence on event-related motor tasks: A functional near-infrared spectroscopy study

Isao Nambu, Takuya Ozawa, Takanori Sato, Takatsugu Aihara, Yusuke Fujiwara, Yohei Otaka, Rieko Osu, Jun Izawa, Yasuhiro Wada

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Functional near-infrared spectroscopy (fNIRS) is a widely utilized neuroimaging tool in fundamental neuroscience research and clinical investigation. Previous research has revealed that task-evoked systemic artifacts mainly originating from the superficial-tissue may preclude the identification of cerebral activation during a given task. We examined the influence of such artifacts on event-related brain activity during a brisk squeezing movement. We estimated task-evoked superficial-tissue hemodynamics from short source-detector distance channels (15 mm) by applying principal component analysis. The estimated superficial-tissue hemodynamics exhibited temporal profiles similar to the canonical cerebral hemodynamic model. Importantly, this task-evoked profile was also observed in data from a block design motor experiment, suggesting a transient increase in superficial-tissue hemodynamics occurs following motor behavior, irrespective of task design. We also confirmed that estimation of event-related cerebral hemodynamics was improved by a simple superficial-tissue hemodynamic artifact removal process using 15-mm short distance channels, compared to the results when no artifact removal was applied. Thus, our results elucidate task design-independent characteristics of superficial- tissue hemodynamics and highlight the need for the application of superficial-tissue hemodynamic artifact removal methods when analyzing fNIRS data obtained during event-related motor tasks.

Original languageEnglish
Article number035008
JournalJournal of Biomedical Optics
Volume22
Issue number3
DOIs
Publication statusPublished - 2017 Mar 1

Fingerprint

hemodynamics
Near infrared spectroscopy
Hemodynamics
infrared spectroscopy
interference
Tissue
artifacts
Neuroimaging
neurology
profiles
principal components analysis
compressing
Principal component analysis
brain
Brain
Chemical activation
activation
Detectors
detectors

Keywords

  • artifact removal
  • event-related design
  • functional near-infrared spectroscopy
  • general linear model
  • superficial-tissue hemodynamics

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Biomedical Engineering

Cite this

Transient increase in systemic interferences in the superficial layer and its influence on event-related motor tasks : A functional near-infrared spectroscopy study. / Nambu, Isao; Ozawa, Takuya; Sato, Takanori; Aihara, Takatsugu; Fujiwara, Yusuke; Otaka, Yohei; Osu, Rieko; Izawa, Jun; Wada, Yasuhiro.

In: Journal of Biomedical Optics, Vol. 22, No. 3, 035008, 01.03.2017.

Research output: Contribution to journalArticle

Nambu, Isao ; Ozawa, Takuya ; Sato, Takanori ; Aihara, Takatsugu ; Fujiwara, Yusuke ; Otaka, Yohei ; Osu, Rieko ; Izawa, Jun ; Wada, Yasuhiro. / Transient increase in systemic interferences in the superficial layer and its influence on event-related motor tasks : A functional near-infrared spectroscopy study. In: Journal of Biomedical Optics. 2017 ; Vol. 22, No. 3.
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