TY - JOUR
T1 - Transparent, conformable, active multielectrode array using organic electrochemical transistors
AU - Lee, Wonryung
AU - Kim, Dongmin
AU - Matsuhisa, Naoji
AU - Nagase, Masae
AU - Sekino, Masaki
AU - Malliaras, George G.
AU - Yokota, Tomoyuki
AU - Someya, Takao
N1 - Funding Information:
ACKNOWLEDGMENTS. We thank Marce Ferro, Pierre Leleux, Jonathan Rivnay, Junhyung Kim, Sunghoon Lee, Robert Nawrocki, Sungjoon Park, and Prof. Makoto Takamiya for the discussions and Prof. Hiromu Yawo for supplying the optogenetic rat. W.L. was supported by the Japan Society for the Promotion of Science (JSPS) through the Program for Leading Graduate Schools. N.M. was supported by the Advanced Leading Graduate Course for Photon Science and a JSPS research fellowship for young scientists. This work was supported by Japan Science and Technology Agency Exploratory Research for Advanced Technology Grant JPMJER1105.
Publisher Copyright:
© 2017, National Academy of Sciences. All rights reserved.
PY - 2017/10/3
Y1 - 2017/10/3
N2 - Mechanically flexible active multielectrode arrays (MEA) have been developed for local signal amplification and high spatial resolution. However, their opaqueness limited optical observation and light stimulation during use. Here, we show a transparent, ultraflexible, and active MEA, which consists of transparent organic electrochemical transistors (OECTs) and transparent Au grid wirings. The transparent OECT is made of Au grid electrodes and has shown comparable performance with OECTs with nontransparent electrodes/wirings. The transparent active MEA realizes the spatial mapping of electrocorticogram electrical signals from an optogenetic rat with 1-mm spacing and shows lower light artifacts than noise level. Our active MEA would open up the possibility of precise investigation of a neural network system with direct light stimulation.
AB - Mechanically flexible active multielectrode arrays (MEA) have been developed for local signal amplification and high spatial resolution. However, their opaqueness limited optical observation and light stimulation during use. Here, we show a transparent, ultraflexible, and active MEA, which consists of transparent organic electrochemical transistors (OECTs) and transparent Au grid wirings. The transparent OECT is made of Au grid electrodes and has shown comparable performance with OECTs with nontransparent electrodes/wirings. The transparent active MEA realizes the spatial mapping of electrocorticogram electrical signals from an optogenetic rat with 1-mm spacing and shows lower light artifacts than noise level. Our active MEA would open up the possibility of precise investigation of a neural network system with direct light stimulation.
KW - Multielectrode array
KW - Optogenetic
KW - Organic electrochemical transistors
KW - Thin films
KW - Transparent electrode
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U2 - 10.1073/pnas.1703886114
DO - 10.1073/pnas.1703886114
M3 - Article
C2 - 28923928
AN - SCOPUS:85030464505
SN - 0027-8424
VL - 114
SP - 10554
EP - 10559
JO - Proceedings of the National Academy of Sciences of the United States of America
JF - Proceedings of the National Academy of Sciences of the United States of America
IS - 40
ER -