Transperineal magnetic resonance image guided prostate biopsy

A. V. D'Amico, C. M. Tempany, R. Cormack, N. Hata, M. Jinzaki, K. Tuncali, M. Weinstein, J. P. Richie

Research output: Contribution to journalArticle

131 Citations (Scopus)

Abstract

Purpose: We report the findings of a transperineal magnetic resonance image (MRI) guided biopsy of the prostate in a man with increasing prostate specific antigen who was not a candidate for a transrectal ultrasound guided biopsy. Materials and Methods: Using an open configuration 0.5 Tesla MRI scanner and pelvic coil, a random sextant sample was obtained under real time MRI guidance from the peripheral zone of the prostate gland as well as a single core from each MRI defined lesion. The patient had previously undergone proctocolectomy for ulcerative colitis and, therefore, was not a candidate for transrectal ultrasound guided biopsy. Prior attempts to make the diagnosis of prostate cancer using a transurethral approach were unsuccessful. Results: The random sextant samples contained benign prostatic hyperplasia, whereas Gleason grade 3 + 3 = 6 adenocarcinoma was confirmed in 15% and 25% of the 2 cores obtained from the MRI targeted specimens of 2 defined lesions. The procedure was well tolerated by the patient. Conclusions: Transperineal MRI guided biopsy is a new technique that may be useful in detecting prostate cancer in men with increasing prostate specific antigen who are not candidates for transrectal ultrasound guided biopsy.

Original languageEnglish
Pages (from-to)385-387
Number of pages3
JournalJournal of Urology
Volume164
Issue number2
DOIs
Publication statusPublished - 2000 Aug

Keywords

  • Biopsy
  • Magnetic resonance imaging
  • Prostate
  • Prostate-specific antigen
  • Prostatic neoplasms

ASJC Scopus subject areas

  • Urology

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  • Cite this

    D'Amico, A. V., Tempany, C. M., Cormack, R., Hata, N., Jinzaki, M., Tuncali, K., Weinstein, M., & Richie, J. P. (2000). Transperineal magnetic resonance image guided prostate biopsy. Journal of Urology, 164(2), 385-387. https://doi.org/10.1016/S0022-5347(05)67366-1