Transplantation of a neurospheroid network onto the rat brain

Midori Kato-Negishi, Yukiko Tsuda, Hiroaki Onoe, Shoji Takeuchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

This paper describes a method to transplant neurospheroid network onto the rat brain. We first patterned the uniform sized neurospheroids on the PDMS microchamber, and cultured for 1-2 weeks. After 2-week culture, the neurospheroids tightly connected each other with extending their neuronal processes (e.g. dendrite, axons) and formed neuronal network. We realized that the neurospheroid network can be transferred from the PDMS microchamber onto the glass plate or the rat brain. These transferred neurospheroid network had also neuronal activities. We believe that this transfer method of neurospheroid network should be a useful model for the tissue engineering and medical transplantation.

Original languageEnglish
Title of host publicationProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Pages1035-1038
Number of pages4
DOIs
Publication statusPublished - 2010
Externally publishedYes
Event23rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2010 - Hong Kong, China
Duration: 2010 Jan 242010 Jan 28

Other

Other23rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2010
CountryChina
CityHong Kong
Period10/1/2410/1/28

Fingerprint

transplantation
rats
brain
Rats
Brain
Transplantation (surgical)
Transplants
Tissue engineering
Glass
axons
tissue engineering
dendrites
glass
Axons

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Mechanical Engineering
  • Condensed Matter Physics
  • Electronic, Optical and Magnetic Materials

Cite this

Kato-Negishi, M., Tsuda, Y., Onoe, H., & Takeuchi, S. (2010). Transplantation of a neurospheroid network onto the rat brain. In Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) (pp. 1035-1038). [5442386] https://doi.org/10.1109/MEMSYS.2010.5442386

Transplantation of a neurospheroid network onto the rat brain. / Kato-Negishi, Midori; Tsuda, Yukiko; Onoe, Hiroaki; Takeuchi, Shoji.

Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2010. p. 1035-1038 5442386.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kato-Negishi, M, Tsuda, Y, Onoe, H & Takeuchi, S 2010, Transplantation of a neurospheroid network onto the rat brain. in Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)., 5442386, pp. 1035-1038, 23rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2010, Hong Kong, China, 10/1/24. https://doi.org/10.1109/MEMSYS.2010.5442386
Kato-Negishi M, Tsuda Y, Onoe H, Takeuchi S. Transplantation of a neurospheroid network onto the rat brain. In Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2010. p. 1035-1038. 5442386 https://doi.org/10.1109/MEMSYS.2010.5442386
Kato-Negishi, Midori ; Tsuda, Yukiko ; Onoe, Hiroaki ; Takeuchi, Shoji. / Transplantation of a neurospheroid network onto the rat brain. Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2010. pp. 1035-1038
@inproceedings{e7c214bd833e489eaed0fa9218fa178f,
title = "Transplantation of a neurospheroid network onto the rat brain",
abstract = "This paper describes a method to transplant neurospheroid network onto the rat brain. We first patterned the uniform sized neurospheroids on the PDMS microchamber, and cultured for 1-2 weeks. After 2-week culture, the neurospheroids tightly connected each other with extending their neuronal processes (e.g. dendrite, axons) and formed neuronal network. We realized that the neurospheroid network can be transferred from the PDMS microchamber onto the glass plate or the rat brain. These transferred neurospheroid network had also neuronal activities. We believe that this transfer method of neurospheroid network should be a useful model for the tissue engineering and medical transplantation.",
author = "Midori Kato-Negishi and Yukiko Tsuda and Hiroaki Onoe and Shoji Takeuchi",
year = "2010",
doi = "10.1109/MEMSYS.2010.5442386",
language = "English",
isbn = "9781424457649",
pages = "1035--1038",
booktitle = "Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)",

}

TY - GEN

T1 - Transplantation of a neurospheroid network onto the rat brain

AU - Kato-Negishi, Midori

AU - Tsuda, Yukiko

AU - Onoe, Hiroaki

AU - Takeuchi, Shoji

PY - 2010

Y1 - 2010

N2 - This paper describes a method to transplant neurospheroid network onto the rat brain. We first patterned the uniform sized neurospheroids on the PDMS microchamber, and cultured for 1-2 weeks. After 2-week culture, the neurospheroids tightly connected each other with extending their neuronal processes (e.g. dendrite, axons) and formed neuronal network. We realized that the neurospheroid network can be transferred from the PDMS microchamber onto the glass plate or the rat brain. These transferred neurospheroid network had also neuronal activities. We believe that this transfer method of neurospheroid network should be a useful model for the tissue engineering and medical transplantation.

AB - This paper describes a method to transplant neurospheroid network onto the rat brain. We first patterned the uniform sized neurospheroids on the PDMS microchamber, and cultured for 1-2 weeks. After 2-week culture, the neurospheroids tightly connected each other with extending their neuronal processes (e.g. dendrite, axons) and formed neuronal network. We realized that the neurospheroid network can be transferred from the PDMS microchamber onto the glass plate or the rat brain. These transferred neurospheroid network had also neuronal activities. We believe that this transfer method of neurospheroid network should be a useful model for the tissue engineering and medical transplantation.

UR - http://www.scopus.com/inward/record.url?scp=77952784944&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77952784944&partnerID=8YFLogxK

U2 - 10.1109/MEMSYS.2010.5442386

DO - 10.1109/MEMSYS.2010.5442386

M3 - Conference contribution

SN - 9781424457649

SP - 1035

EP - 1038

BT - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)

ER -