Transplantation of a neurospheroid network onto the rat brain

Midori Kato-Negishi; Yukiko Tsuda; Hiroaki Onoe; Shoji Takeuchi

doi:10.1109/MEMSYS.2010.5442386

Transplantation of a neurospheroid network onto the rat brain

Midori Kato-Negishi, Yukiko Tsuda, Hiroaki Onoe, Shoji Takeuchi

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

2 Citations (Scopus)

Abstract

This paper describes a method to transplant neurospheroid network onto the rat brain. We first patterned the uniform sized neurospheroids on the PDMS microchamber, and cultured for 1-2 weeks. After 2-week culture, the neurospheroids tightly connected each other with extending their neuronal processes (e.g. dendrite, axons) and formed neuronal network. We realized that the neurospheroid network can be transferred from the PDMS microchamber onto the glass plate or the rat brain. These transferred neurospheroid network had also neuronal activities. We believe that this transfer method of neurospheroid network should be a useful model for the tissue engineering and medical transplantation.

Original language	English
Title of host publication	MEMS 2010 - The 23rd IEEE International Conference on Micro Electro Mechanical Systems, Technical Digest
Pages	1035-1038
Number of pages	4
DOIs	https://doi.org/10.1109/MEMSYS.2010.5442386
Publication status	Published - 2010 Jun 1
Externally published	Yes
Event	23rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2010 - Hong Kong, China Duration: 2010 Jan 24 → 2010 Jan 28

Publication series

Name	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)	1084-6999

Other

Other	23rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2010
Country/Territory	China
City	Hong Kong
Period	10/1/24 → 10/1/28

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Mechanical Engineering
Electrical and Electronic Engineering

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10.1109/MEMSYS.2010.5442386

Cite this

Kato-Negishi, M., Tsuda, Y., Onoe, H., & Takeuchi, S. (2010). Transplantation of a neurospheroid network onto the rat brain. In MEMS 2010 - The 23rd IEEE International Conference on Micro Electro Mechanical Systems, Technical Digest (pp. 1035-1038). [5442386] (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2010.5442386

Transplantation of a neurospheroid network onto the rat brain. / Kato-Negishi, Midori; Tsuda, Yukiko; Onoe, Hiroaki et al.
MEMS 2010 - The 23rd IEEE International Conference on Micro Electro Mechanical Systems, Technical Digest. 2010. p. 1035-1038 5442386 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Kato-Negishi, M, Tsuda, Y, Onoe, H & Takeuchi, S 2010, Transplantation of a neurospheroid network onto the rat brain. in MEMS 2010 - The 23rd IEEE International Conference on Micro Electro Mechanical Systems, Technical Digest., 5442386, Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), pp. 1035-1038, 23rd IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2010, Hong Kong, China, 10/1/24. https://doi.org/10.1109/MEMSYS.2010.5442386

Kato-Negishi M, Tsuda Y, Onoe H, Takeuchi S. Transplantation of a neurospheroid network onto the rat brain. In MEMS 2010 - The 23rd IEEE International Conference on Micro Electro Mechanical Systems, Technical Digest. 2010. p. 1035-1038. 5442386. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). doi: 10.1109/MEMSYS.2010.5442386

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Transplantation of a neurospheroid network onto the rat brain

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