Transplantation of neural progenitor cells into the human CNS

Research output: Contribution to journalShort surveypeer-review

1 Citation (Scopus)

Abstract

The development of regenerative medicine for spinal cord injury (SCI) and intractable diseases of the nervous system using neural progenitor cells (NPCs) has shown great promise, and several clinical trials have begun. In addition, ex vivo gene therapy using genetically engineered NPCs was recently initiated in the clinical setting by Baloh et al., putatively showing enhanced therapeutic effects. Thus, the era of next-generation NPC transplantation therapy is beginning to dawn.

Original languageEnglish
Pages (from-to)897-899
Number of pages3
JournalTrends in Molecular Medicine
Volume28
Issue number11
DOIs
Publication statusPublished - 2022 Nov

Keywords

  • ALS
  • chemogenetics
  • engineered neural progenitor cells
  • ex vivo gene therapy
  • GDNF
  • spinal cord injury (SCI)

ASJC Scopus subject areas

  • Molecular Medicine
  • Molecular Biology

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