Transpupillary thermotherapy for atypical central serous chorioretinopathy

Ryosuke Kawamura, Hidenao Ideta, Hideyuki Hori, Kenya Yuki, Tsuyoshi Uno, Tatsurou Tanabe, Kazuo Tsubota, Tsutomu Kawasaki

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background: Central serous chorioretinopathy (CSC) has been traditionally treated with laser photocoagulation. We thought that transpupillary thermotherapy (TTT) utilizing a lower temperature than that of conventional laser photocoagulation might minimize permanent retinal and choroidal damage. Studies suggest that undesirable effects on vision due to TTT are minimal even if it is applied to foveal and/or parafoveal lesions when TTT requires a larger irradiation spot. The aim of this study was to evaluate the efficacy of TTT in the management of atypical CSC. Methods: We defined atypical CSC as bullous retinal detachment with diffuse or several leakages, severe leakage with fibrin formation under serous retinal detachment, or leakage within a pigment epithelium detachment. Eight consecutive patients with atypical CSC underwent visual acuity testing, ophthalmic examination, color photography, fluorescein angiography, and optical coherence tomography to evaluate the results of transpupillary thermotherapy. Retreatment of atypical CSC was based on ophthalmic examination, optical coherence tomography, and fluorescein angiography. TTT was performed on the leaking spots shown in fluorescein angiography, with a power of 50-250 mW, spot size of 500-1200 μm, and exposure time of 13-60 seconds to minimize retinal damage. Results: In five of eight affected eyes, serous detachments completely resolved within 1 month after the initial TTT. One eye had persistent subretinal fluid and required a second TTT treatment. Two eyes showed no resolution of CSC and were treated by conventional photocoagulation. Initial best-corrected visual acuity (BCVA) ranged from 20/600 to 20/20 (mean, 20/40; median, 20/30). Final BCVA ranged from 20/200 to 20/20 (mean, 20/25; median, 20/20). BCVA improved in all cases. Only two eyes with persistent subretinal fibrin and existing retinal pigment epithelial alternations in macular area showed limited improvement of BCVA despite the absence of subretinal exudation. The presence of retinal attachment was confirmed by optical coherence tomography in six eyes (75%). Conclusions: TTT seems to be effective for the treatment of atypical CSC in the short term. Additional studies are necessary to evaluate the long-term effectiveness and safety.

Original languageEnglish
Pages (from-to)175-179
Number of pages5
JournalClinical Ophthalmology
Volume6
Issue number1
DOIs
Publication statusPublished - 2012

Fingerprint

Central Serous Chorioretinopathy
Induced Hyperthermia
Visual Acuity
Fluorescein Angiography
Light Coagulation
Optical Coherence Tomography
Retinal Detachment
Fibrin
Lasers
Eye Color
Subretinal Fluid
Retreatment
Retinal Pigments
Photography
Epithelium
Safety

Keywords

  • Central serous chorioretinopathy
  • Fluorescein angiography
  • Optical coherence tomography
  • Serous detachment
  • Transpupillary thermotherapy

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Kawamura, R., Ideta, H., Hori, H., Yuki, K., Uno, T., Tanabe, T., ... Kawasaki, T. (2012). Transpupillary thermotherapy for atypical central serous chorioretinopathy. Clinical Ophthalmology, 6(1), 175-179. https://doi.org/10.2147/OPTH.S28239

Transpupillary thermotherapy for atypical central serous chorioretinopathy. / Kawamura, Ryosuke; Ideta, Hidenao; Hori, Hideyuki; Yuki, Kenya; Uno, Tsuyoshi; Tanabe, Tatsurou; Tsubota, Kazuo; Kawasaki, Tsutomu.

In: Clinical Ophthalmology, Vol. 6, No. 1, 2012, p. 175-179.

Research output: Contribution to journalArticle

Kawamura, R, Ideta, H, Hori, H, Yuki, K, Uno, T, Tanabe, T, Tsubota, K & Kawasaki, T 2012, 'Transpupillary thermotherapy for atypical central serous chorioretinopathy', Clinical Ophthalmology, vol. 6, no. 1, pp. 175-179. https://doi.org/10.2147/OPTH.S28239
Kawamura, Ryosuke ; Ideta, Hidenao ; Hori, Hideyuki ; Yuki, Kenya ; Uno, Tsuyoshi ; Tanabe, Tatsurou ; Tsubota, Kazuo ; Kawasaki, Tsutomu. / Transpupillary thermotherapy for atypical central serous chorioretinopathy. In: Clinical Ophthalmology. 2012 ; Vol. 6, No. 1. pp. 175-179.
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