Treatment of burns by grafting of cultured epithelium

T. Nagase, N. Kumagai, K. Matsuzaki, M. Tanabe

Research output: Contribution to journalArticle

Abstract

The most serious problem in the treatment of extensive burns is a lack of sufficient healthy skin for coverage of the affected area. Several methods have been used for the coverage of extensive burn wounds. The grafting of cultured epithelium is a potentially effective method for a permanent covering of the wound, particularly in patients with extensive burns. The condition of the recipient site is the most important factor in the success of cultured epithelium grafting and the preservation of the dermis or dermal components in the burn area will enhance the grafting process. We recommend that prior to the grafting of cultured epithelial cells, the burn wound should be excised and covered with allografts or artificial skin during the first two weeks after admission. An allograft of cultured epithelium is also useful. This method accelerates the epithelialization of both the burn and donor sites. It is expected that cultured epithelial cell grafts will prove to be an effective treatment for not only extensive burns but also to epithelialize small area burn wounds.

Original languageEnglish
Pages (from-to)1091-1096
Number of pages6
JournalJapanese Journal of Plastic and Reconstructive Surgery
Volume43
Issue number11
Publication statusPublished - 2000
Externally publishedYes

Fingerprint

Burns
Epithelium
Wounds and Injuries
Allografts
Cultured Cells
Epithelial Cells
Artificial Skin
Skin
Therapeutics
Dermis
Tissue Donors
Transplants

ASJC Scopus subject areas

  • Surgery

Cite this

Nagase, T., Kumagai, N., Matsuzaki, K., & Tanabe, M. (2000). Treatment of burns by grafting of cultured epithelium. Japanese Journal of Plastic and Reconstructive Surgery, 43(11), 1091-1096.

Treatment of burns by grafting of cultured epithelium. / Nagase, T.; Kumagai, N.; Matsuzaki, K.; Tanabe, M.

In: Japanese Journal of Plastic and Reconstructive Surgery, Vol. 43, No. 11, 2000, p. 1091-1096.

Research output: Contribution to journalArticle

Nagase, T, Kumagai, N, Matsuzaki, K & Tanabe, M 2000, 'Treatment of burns by grafting of cultured epithelium', Japanese Journal of Plastic and Reconstructive Surgery, vol. 43, no. 11, pp. 1091-1096.
Nagase, T. ; Kumagai, N. ; Matsuzaki, K. ; Tanabe, M. / Treatment of burns by grafting of cultured epithelium. In: Japanese Journal of Plastic and Reconstructive Surgery. 2000 ; Vol. 43, No. 11. pp. 1091-1096.
@article{e1e55058680f4c33ab039aec78d0b4ea,
title = "Treatment of burns by grafting of cultured epithelium",
abstract = "The most serious problem in the treatment of extensive burns is a lack of sufficient healthy skin for coverage of the affected area. Several methods have been used for the coverage of extensive burn wounds. The grafting of cultured epithelium is a potentially effective method for a permanent covering of the wound, particularly in patients with extensive burns. The condition of the recipient site is the most important factor in the success of cultured epithelium grafting and the preservation of the dermis or dermal components in the burn area will enhance the grafting process. We recommend that prior to the grafting of cultured epithelial cells, the burn wound should be excised and covered with allografts or artificial skin during the first two weeks after admission. An allograft of cultured epithelium is also useful. This method accelerates the epithelialization of both the burn and donor sites. It is expected that cultured epithelial cell grafts will prove to be an effective treatment for not only extensive burns but also to epithelialize small area burn wounds.",
author = "T. Nagase and N. Kumagai and K. Matsuzaki and M. Tanabe",
year = "2000",
language = "English",
volume = "43",
pages = "1091--1096",
journal = "Japanese Journal of Plastic Surgery",
issn = "0021-5228",
publisher = "Kokuseido Publishing Co. Ltd",
number = "11",

}

TY - JOUR

T1 - Treatment of burns by grafting of cultured epithelium

AU - Nagase, T.

AU - Kumagai, N.

AU - Matsuzaki, K.

AU - Tanabe, M.

PY - 2000

Y1 - 2000

N2 - The most serious problem in the treatment of extensive burns is a lack of sufficient healthy skin for coverage of the affected area. Several methods have been used for the coverage of extensive burn wounds. The grafting of cultured epithelium is a potentially effective method for a permanent covering of the wound, particularly in patients with extensive burns. The condition of the recipient site is the most important factor in the success of cultured epithelium grafting and the preservation of the dermis or dermal components in the burn area will enhance the grafting process. We recommend that prior to the grafting of cultured epithelial cells, the burn wound should be excised and covered with allografts or artificial skin during the first two weeks after admission. An allograft of cultured epithelium is also useful. This method accelerates the epithelialization of both the burn and donor sites. It is expected that cultured epithelial cell grafts will prove to be an effective treatment for not only extensive burns but also to epithelialize small area burn wounds.

AB - The most serious problem in the treatment of extensive burns is a lack of sufficient healthy skin for coverage of the affected area. Several methods have been used for the coverage of extensive burn wounds. The grafting of cultured epithelium is a potentially effective method for a permanent covering of the wound, particularly in patients with extensive burns. The condition of the recipient site is the most important factor in the success of cultured epithelium grafting and the preservation of the dermis or dermal components in the burn area will enhance the grafting process. We recommend that prior to the grafting of cultured epithelial cells, the burn wound should be excised and covered with allografts or artificial skin during the first two weeks after admission. An allograft of cultured epithelium is also useful. This method accelerates the epithelialization of both the burn and donor sites. It is expected that cultured epithelial cell grafts will prove to be an effective treatment for not only extensive burns but also to epithelialize small area burn wounds.

UR - http://www.scopus.com/inward/record.url?scp=0033634756&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033634756&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0033634756

VL - 43

SP - 1091

EP - 1096

JO - Japanese Journal of Plastic Surgery

JF - Japanese Journal of Plastic Surgery

SN - 0021-5228

IS - 11

ER -