Abstract
We analyzed the clinical efficacy and safety of chemotherapy using S-1 plus weekly CDDP( w-CS therapy) for unresectable gastric cancer. Twenty one patients were treated with this treatment. S-1 80 mg/m2/day was administered for 2 weeks followed by a 1-week rest. CDDP 20 mg/m2 was injected intravenously on day 1 and 8. The overall response rate was 52. 3%. The disease control rate was 85.7%. Grade 3 or 4 major toxicity comprised neutropenia (14.2%), thrombocytopenia (4.7%) and plasma creatinine elevation (4.7%). w-CS therapy is satisfied resulting with efficacy and safety. Thus, future clinical trials and accumulation of futher cases are warranted.
Original language | English |
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Pages (from-to) | 2351-2353 |
Number of pages | 3 |
Journal | Gan to kagaku ryoho. Cancer & chemotherapy |
Volume | 38 |
Issue number | 12 |
Publication status | Published - 2011 Nov |
Externally published | Yes |
ASJC Scopus subject areas
- Oncology
- Cancer Research